Exclusive AAV Antibodies for AAV-based projects

AAV antibodies are useful tools for monitoring and optimizing entire AAV manufacturing processes. 
You can choose from PROGEN’s portfolio of exclusive AAV antibodies for the most commonly used AAV serotypes.

PROGEN has been manufacturing antibodies since 1983 and our commitment to quality has always been a focus. In 2010 PROGEN was awarded with the DIN EN ISO13485 certification.

 

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Using AAV Capsid and Particle Antibodies

Watch our short 90 second video for a quick overview of capsid and particle antibodies and how they can be used in your next AAV gene therapy project.

AAV Antibodies FAQs

Yes, our AAV particle antibodies detect conformational epitopes only present on assembled capsids.

You can find all AAV particle antibodies here.

In contrast, AAV capsid protein antibodies recognize linear epitopes present on denatured VP proteins.

You can find all AAV capsid protein antibodies here.

Yes, PROGEN offers a selection of AAV antibodies in 10 µg sample sizes. You can find all available AAV antibodies here: AAV Antibodies

PROGEN offers a wide range of AAV antibodies either detecting a linear epitope (AAV capsid protein antibodies), a conformational epitope (AAV particle antibodies) or a AAV replicase.

These antibodies are provided in different quantities and formats (e.g. purified and supernatant). A selection of AAV antibodies are also available in 10 µg sample sizes. You can find all available AAV antibodies here: AAV Antibodies.

Anti-Adeno-Associated Virus Capsid Proteins Antibodies

For more information on the antibody binding epitopes of the capsid protein antibodies A1, B1 and A69 see the table below summarizing the published data from the following publication on the specific antibody binding sites:

Table Binding Sites of the AAV capsid protein antibodies

Wobus, C. E. et al. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 74, 9281–93 (2000).

Anti-Adeno-Associated Virus Particle Antibodies

For more information on the antibody binding epitopes on assembled AAV1, 2, 5, 8 and 9 capsids, see the tables below summarizing the published data from the following publications on the specific antibody binding sites:

summary binding epitopes


EM structures of assembled AAV1, 2, 4, 5, 6, and 8 capsids with Fab-fragments are available in the following publications: