Disease related

anti-Annexin A1 mouse monoclonal, IHC512, purified

Cat. No. 691739

Available, delivery time 1-7 days

€470.00*

Key Features
  • Mouse monoclonal
  • Suitable for IHC
  • Reacts with human
  • Isotype: IgG1
Product description
Quantity 1 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application IHC
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Clone IHC512
Immunogen Recombinant Human Annexin A1
Formulation Tris pH 7.3-7.7 with 1% BSA and 0.09% sodium azide
UniprotID P04083 (Human)
Synonym Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35, ANXA1, ANX1, LPC1
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - paraffin 1:50-1:200 (microwave treatment recommended)
Background
Annexin A1 (ANXA1) is a membrane protein that plays a role in innate and adaptive immunity by controlling the biosynthesis of inflammation, prostaglandins, and leukotriene mediators. This target is overexpressed in 97% of all samples from patients with hairy cell leukemia, and is absent in other B-cell lymphomas. High ANXA1 expression is frequently associated with advanced stage esophageal and esophagogastric junction adenocarcinoma, and is also linked to advanced and metastatic disease states.
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