Disease related

anti-Calprotectin S100A8/A9 Complex mouse monoclonal, 69-6-1, lyophilized, purified

Cat. No. 610191

Available, delivery time 1-7 days

€274.00*

Key Features
  • Mouse monoclonal
  • Suitable for ELISA, IHC and WB
  • Reacts with human
  • Isotype: IgG2b
Product description
Antibody Type Monoclonal
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Application ELISA, IHC, WB
Purification Affinity chromatography
Reactivity Human
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone 69-6-1
Immunogen Recombinant protein
Concentration 100 µg/ml after reconstitution with 1 ml dist. water
Formulation Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - paraffin 1:100-1:300 (microwave treatment recommended)
ELISA 1:50
Western Blot (WB) 1:1,000
Background

Calprotectin is a functional heterocomplex of small EF hand calcium binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cells and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via its binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammation and was also linked to cancer formation.

Tissue expression: strong expression in myeloid cells and psoriatic keratinocytes.

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anti-Calprotectin S100A9 & S100A8/A9 Complex mouse monoclonal, 23-3-4, lyophilized, purified
Cat. No. 610188
  • Mouse monoclonal
  • Suitable for ELISA, IHC and WB
  • Reacts with human
  • Isotype: IgG2b

€274.00*