Disease related

anti-Cdk7 mouse monoclonal, Mo-1.1, lyophilized, purified

Cat. No. 61063

Available, delivery time 1-7 days

€165.00*

Key Features
  • Mouse monoclonal
  • Suitable for FACS, ICC/IF, IHC, IP and WB
  • Reacts with human and mouse
  • Isoytpe: IgG2b
Product description
Quantity 50 µg
Antibody Type Monoclonal
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Application FACS, ICC/IF, IHC, IP, WB
Purification Affinity chromatography
Reactivity Human, Mouse
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone MO-1.1
Immunogen Recombinant C-terminal 221 aa fragment of human wild-type cdk7/CAK (cyclin activating kinase)
Concentration 50 µg/ml after reconstitution with 1 ml dist. water
Formulation Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
UniprotID P50613 (Human),Q03147 (Mouse)
Synonym Cyclin-dependent kinase 7, EC 2.7.11.22, EC 2.7.11.23, 39 kDa protein kinase, p39 Mo15, CDK-activating kinase 1, Cell division protein kinase 7, Serine/threonine-protein kinase 1, TFIIH basal transcription factor complex kinase subunit, CDK7, CAK, CAK1, CDKN7, MO15, STK1
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Assay dependent
Immunohistochemistry (IHC) - frozen 1:10-1:20
Flow Cytometry (FACS) Assay dependent
Immunoprecipitation (IP) Assay dependent
Western Blot (WB) Assay dependent
Background

Mo-1.1 recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase. The antibody is useful for cell cycle analysis, cell proliferation studies and for immunohistochemistry.

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