Disease related

anti-Cyclin-Dependent Kinase 6 mouse monoclonal, DCS-83, lyophilized, purified

Cat. No. 610103

Available, delivery time 1-7 days

€158.00*

Key Features
  • Mouse monoclonal
  • Suitable for IHC, IP and WB
  • Reacts with human
  • Isotype: IgG1
Product description
Quantity 100 µg
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application IHC, IP, WB
Purification Affinity chromatography
Reactivity Human
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone DCS-83
Immunogen Human recombinant full-length cdk6 polypeptide
Concentration 100 µg/ml after reconstitution with 1 ml dist. water
Formulation Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
UniprotID Q00534 (Human)
Synonym Cyclin-dependent kinase 6, EC 2.7.11.22, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE, CDK6, CDKN6
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:10
Immunohistochemistry (IHC) - paraffin 1:10 (microwave treatment recommended)
Immunoprecipitation (IP) Assay dependent
Western Blot (WB) Assay dependent
Background
The anti-Cyclin-Dependent Kinase 6 (Cdk6) monoclonal DCS-83 antibody reacts specifically with Cdk6 kinase, which can substitute for Cdk4. Cdk6 is highly expressed in some lymphoid tumor and sarcoma cell lines (ML-1 and U-2-OS resp.). Positive staining found in head and neck tumors.
References/Publications (1)
Publication
Species
Application
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