anti-Interferon alpha 1 mouse monoclonal, 2-48, purified

Cat. No. 691510

Available, delivery time 1-7 days

€340.00*

Key Features
  • Mouse monoclonal
  • Suitable for ELISA, IHC and WB
  • Reacts with human
  • Isotype: IgG1 kappa
Product description
Quantity 1 ml (100 µg/ml)
Antibody Type Monoclonal
Host Mouse
Isotype IgG1 kappa
Conjugate Unconjugated
Application ELISA, IHC, WB
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Clone 2-48
Immunogen E. coli derived recombinant human interferon alpha 1
Concentration 100 µg/ml
Formulation PBS with 0.02% sodium azide
UniprotID P01562 (Human)
Synonym Interferon alpha-1/13, IFN-alpha-1/13, Interferon alpha-D, LeIF D, IFNA1, IFNA13
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:50-1:100 (1-2 µg/ml)
ELISA Assay dependent
Western Blot (WB) 1:50-1:100 (1-2 µg/ml)
Background

The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The interferon alpha (IFN alpha) family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFN alpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFN alpha include cytopathic effect blocking by viruses such as VSV, SFV and BMCV on their target cells. A number of receptors for IFN alpha are now known and seem to be expressed on most cell types. 2-48 is specific for human IFN alpha 1 and does not cross react with human IFN alpha 2.

Positive control: human IFN alpha 1.

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