Disease related
Frequently used

anti-Keratin K17 mouse monoclonal, Ks17.E3, lyophilized, purified

Liquid

Liquid

Lyophilized

Sample

Cat. No. 61036

Available, delivery time 1-7 days

€207.00*

Key Features
  • Purified, lyophilized
  • Mouse monoclonal
  • Suitable for IHC and WB
  • Reacts with human, rat
  • Isotype: IgG2b
Product description
Quantity 50 µg
Antibody Type Monoclonal
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Application IHC, WB
Purification Affinity chromatography
Reactivity Human, Rat
Storage before reconstitution 2-8°C until indicated expiry date
Storage after reconstitution Up to 3 months at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone Ks17.E3
Immunogen Human keratin K17 of 46 kDa
Concentration 50 µg/ml after reconstitution with 1 ml dist. water
Formulation Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
UniprotID Q04695 (Human),Q6IFU8 (Rat)
Synonym Keratin, type I cytoskeletal 17, 39.1, Cytokeratin-17, CK-17, Keratin-17, K17, KRT17
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:10-1:50
Immunohistochemistry (IHC) - paraffin 1:10-1:50 (microwave treatment recommended)
Western Blot (WB) Assay dependent
Background

Ks 17.E3 represents an excellent marker to distinguish myoepithelial cells (positive for K17) from luminal epithelium of various glands (mammary, sweat, salivary, bronchial, tracheal, laryngeal, esophageal) and benign from malignant forms of e.g. mammary gland tumors.
In the epidermis suprabasal staining is found only in cornifying regions and in the outer root sheath of hair follicles.
Tested reactivity on cultured cell lines: HeLa, A-431.
Tumors specifically detected: benign tumors of mammary gland; most malignant forms of mammary tumors are negative for keratin K17.

References/Publications (15)
Publication
Species
Application
Downloads
File
Category
Size
Filetype
Category Protocol
Size 924.86 KB
Filetype pdf
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