Disease related

anti-Keratin K18 mouse monoclonal, RGE53, supernatant

Cat. No. 10500

Available, delivery time 1-7 days

€235.00*

Key Features
  • Mouse monoclonal
  • Suitable for IHC on frozen sections and WB
  • Reacts with chicken, dog, human, mouse, pig, rabbit and rat
  • Isotype: IgG1
Product description
Quantity 1 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application IHC, WB
Purification Hybridoma cell culture supernatant
Reactivity Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone RGE53
Immunogen Isolated from HeLa cells
Formulation Contains 0.1% sodium azide
UniprotID A0A1D5PHS2 (Chicken),P05783 (Human),P05784 (Mouse),F1SGG1 (Pig),H0UYZ2 (Guinea pig),Q5BJY9 (Rat)
Synonym Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18, PIG46
Note Centrifuge prior to opening
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:5-1:10
Western Blot (WB) Assay dependent
Background

RGE 53 specifically recognizes simple and glandular epithelial cells from the gastrointestinal tract, the respiratory tract and the urogenital tract, as well as endocrine and exocrine tissues and myoepithelial cells. No reaction with stratified squamous epithelia. In the transitional epithelium of the bladder RGE 53 reacts only with superficial (umbrella) cells. The antibody is useful for the discrimination of adenocarcinomas and mesotheliomas from squamous cell carcinomas and non-epithelial tumors. Polypeptide reacting: 45 kD keratin K18 (formerly also designated cytokeratin 18).

Positive control: Adenocarcinoma

References/Publications (3)
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