anti-Keratin K6 (C-terminus) guinea pig polyclonal, serum

Cat. No. GP91

Available, delivery time 1-7 days

€256.00*

Key Features
  • Guinea pig polyclonal
  • Suitable for IHC
  • Reacts with human and mouse
Product description
Quantity 100 µl
Antibody Type Polyclonal
Host Guinea pig
Conjugate Unconjugated
Application IHC
Purification Stabilized antiserum
Reactivity Human, Mouse
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Immunogen Synthetic peptide of human keratin K6 (C-SSTIKYTTTSS), coupled to KLH
Formulation Contains 0.09% sodium azide and 0.5% BSA
UniprotID P02538 (Human),P50446 (Mouse)
Synonym Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Cytokeratin-6D, CK-6D, Keratin-6A, K6A, Type-II keratin Kb6, allergen Hom s 5, KRT6A, K6A, KRT6D
Note Centrifuge prior to opening
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:100-1:200
Immunohistochemistry (IHC) - paraffin 1:100-1:200 (microwave treatment recommended)
Background

In immunohistochemistry, the antibody detects keratin K6 in non-keratinized squamous epithelia, follicular outer root sheath and proliferating cells of epidermis (e.g. within psoriatic lesions). It is completely negative on non-stratified epithelia.
Suitable for discrimination of keratinizing and non-keratinizing squamous cell carcinoma versus e.g. poorly differentiated adenocarcinoma.

Reactive polypeptide: human type II (basic) keratin K6 (formerly also designated cytokeratin 6); MW 56,000 (pI 7.8).

Positive control: human psoriatic skin; rete ridges of foot sole.

References/Publications (1)
Publication
Species
Application
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Category
Size
Filetype
Category Protocol
Size 917.17 KB
Filetype pdf
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