anti-Keratin K6 (C-terminus) guinea pig polyclonal, serum
- Guinea pig polyclonal
- Suitable for IHC
- Reacts with human and mouse
|Storage||Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles|
|Intended use||Research use only|
|Immunogen||Synthetic peptide of human keratin K6 (C-SSTIKYTTTSS), coupled to KLH|
|Formulation||Contains 0.09% sodium azide and 0.5% BSA|
|UniprotID||P02538 (Human),P50446 (Mouse)|
|Synonym||Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Cytokeratin-6D, CK-6D, Keratin-6A, K6A, Type-II keratin Kb6, allergen Hom s 5, KRT6A, K6A, KRT6D|
|Note||Centrifuge prior to opening|
|Tested applications||Tested dilutions|
|Immunohistochemistry (IHC) - frozen||1:100-1:200|
|Immunohistochemistry (IHC) - paraffin||1:100-1:200 (microwave treatment recommended)|
In immunohistochemistry, the antibody detects keratin K6 in non-keratinized squamous epithelia, follicular outer root sheath and proliferating cells of epidermis (e.g. within psoriatic lesions). It is completely negative on non-stratified epithelia.
Suitable for discrimination of keratinizing and non-keratinizing squamous cell carcinoma versus e.g. poorly differentiated adenocarcinoma.
Reactive polypeptide: human type II (basic) keratin K6 (formerly also designated cytokeratin 6); MW 56,000 (pI 7.8).
Positive control: human psoriatic skin; rete ridges of foot sole.
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- Purified, lyophilized
- Mouse monoclonal
- Suitable for IHC and WB
- Reacts with human, mouse and rat
- Isotype: IgG1