Disease related

anti-Keratin K8 mouse monoclonal, Ks8-17.2, supernatant

Cat. No. 65130

Available, delivery time 1-7 days

€143.00*

Key Features
  • Mouse monclonal
  • Suitable for ICC/IF, IHC and WB
  • Reacts with bovine, hamster, human and rat
  • Isotype: IgG1
Product description
Quantity 5 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application ICC/IF, IHC, WB
Purification Hybridoma cell culture supernatant
Reactivity Bovine, Hamster, Human, Rat
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone Ks8-17.2
Immunogen Cytoskeletal proteins from human tumor cell line MCF-7
Formulation Contains 0.09% sodium azide
UniprotID P05786 (Bovine), P05787 (Human), Q10758 (Rat)
Synonym Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8, CYK8
Applications
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Assay dependent
Immunohistochemistry (IHC) - frozen Ready-to-use
Western Blot (WB) Assay dependent
Background

Ks 8-17.2 represents an excellent marker to discriminate simple epithelia from those of different origin.
Tumors specifically detected: all adeno-CA tested; undifferentiated CA; cervix CA; hepatocellular CA.
Polypeptide reacting: Mr 52,500 polypeptide (keratin K8; formerly also designated cytokeratin 8) of human epithelia.
Reactivity on cultured cell lines: MCF-7, HeLa, A-431, PLC, Detroit 562.

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