anti-LDL Receptor rabbit polyclonal, Biotin Conjugate

Biotin

Serum

Cat. No. 61599

Available, delivery time 1-7 days

€322.00*

Key Features
  • Biotin conjugate
  • Rabbit polyclonal
  • Suitable for FACS and Receptor Binding Assays
  • Reacts with human
Product description
Quantity 250 µl
Antibody Type Polyclonal
Host Rabbit
Isotype IgG
Conjugate Biotin
Application FACS, Receptor binding assay
Purification Affinity chromatography
Reactivity Human
Storage 2-8°C
Intended use Research use only
Immunogen Specific synthetic peptide (sequence not conserved in VLDL receptor and LRP) of the human LDL receptor extracellular domain (epitope between residues nos. 184-195, the linker region between repeats 4 and 5)
Formulation PBS pH 7.4 with penicillin/streptomycin
UniprotID P01130 (Human), P01131 (Bovine), P35951 (Mouse), P35952 (Rat)
Synonym Low-density lipoprotein receptor, LDL receptor, LDLR
Note Centrifuge prior to opening
Applications
Tested applications Tested dilutions
Flow Cytometry (FACS) 1:10
Receptor Binding Assays Assay dependent
Background

The LDL receptor (160 kDa mature or glycosylated receptor; 120 kDa precursor or unglycosylated receptor) plays a key role in cellular cholesterol homeostasis.
The antibody to LDLR reacts specifically with human LDLR and is suitable for use in flow cytometry and immunoblotting. The antibody does not inhibit binding of LDL.
In immunoblotting, the antibody recognizes the 160 kDa band of LDLR and a 120 kDa band of the LDLR precursor from fibroblasts, hepatocytes, and monocytic cells cultured in the presence of lipoprotein-deficient serum.

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Category Protocol
Size 925.08 KB
Filetype pdf
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