anti-RAP rabbit polyclonal, serum

Cat. No. 61098

Available, delivery time 1-7 days

€202.00*

Key Features
  • Rabbit polyclonal
  • Suitable for IHC, receptor binding assay and WB
  • Reacts with chicken, human and rat
Product description
Quantity 250 µl
Antibody Type Polyclonal
Host Rabbit
Conjugate Unconjugated
Application IHC, Receptor binding assay, WB
Purification Stabilized antiserum
Reactivity Chicken, Human, Rat
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Immunogen Recombinant human RAP (receptor-associated protein)
Formulation Contains 0.09% sodium azide and 0.5% BSA
UniprotID P62834 (Human),P62836 (Rat)
Synonym Ras-related protein Rap-1A, EC 3.6.5.2, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1, RAP1A, KREV1
Note Centrifuge prior to opening
Applications
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:50–1:100
Immunohistochemistry (IHC) - paraffin 1:50–1:100 (microwave treatment recommended)
Receptor Binding Assays Assay dependent
Western Blot (WB) Assay dependent
Background

The antibody binds to an epitope of the C-terminal part of RAP, a sequence common to the human VLDL receptor superfamily (glycoprotein 330 and LRP), the chicken oocyte receptor for VLDL and vitellogenin (LR8), and glycoprotein 330/megalin from rat. No reaction with LDL receptor. The antibody interferes with binding of VLDL and vitellogenin receptor. Binding is Ca2+-dependent with LR8.

Antigen recognized in species:

human RAP, CD91 (LRP), VLDL-R
chicken LR8
rat gp330
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