Alternative Products
Cat. No. | Product Name | Format | Quantity | Price |
---|---|---|---|---|
610160 |
anti-AAV8 (intact particle) mouse monoclonal, ADK8 |
lyophilized, purified | 50 µg |
$438.00
Excl. VAT, excl. Shipping Cost
|
610160S |
anti-AAV8 (intact particle) mouse monoclonal, ADK8 |
lyophilized, purified, sample | 10 µg |
$131.00
Excl. VAT, excl. Shipping Cost
|
615160 |
anti-AAV8 (intact particle) mouse monoclonal, ADK8 |
Biotin Conjugate | 750 µL |
$287.00
Excl. VAT, excl. Shipping Cost
|
Product description
Host | mouse |
---|---|
Antibody Type | monoclonal |
Isotype | IgG2a kappa |
Clone | ADK8 |
Immunogen | AAV8 capsids |
Purification | hybridoma cell culture supernatant |
Conjugate | unconjugated |
Formulation | contains 0.09% sodium azide |
Storage | short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles |
Intended use | Research use only |
Tested species reactivity | AAV1, AAV3, AAV7, AAV8, AAVrh10, AAVrh74, Anc80 |
Applications
Tested applications | Tested dilutions |
---|---|
Dot Blot | assay dependent (non-denaturing conditions) |
ELISA | assay dependent |
Immunocytochemistry (ICC)/ Immunofluorescence (IF) | assay dependent |
Immunoprecipitation (IP) | assay dependent |
Neutralization Assay | assay dependent |
Background
Details
For characterization of different stages of infection and very useful for the analysis of the AAV assembly process. ADK8 specifically reacts with AAV1, AAV3, AAV7, AAV8, AAVrh10, AAVrh74 and Anc80, empty and full capsids. Recognizes a conformational epitope of assembled capsids. Predicted binding site: residues 586-LQQQNT-591 (Gurda et al., 2012). The antibody cannot be used for immunoblotting using denaturing conditions.
The antibody is also useful for neutralizing experiments.
Gurda BL, et al. Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8. J Virology 86, 7739-7751 (2012).
Limited Use Label License: Research Use Only
Product is exclusively licensed to PROGEN Biotechnik GmbH. The use of these products for the development, manufacturing and sale of secondary products/derivatives which are based on the purchased products and/or which include the purchased product require a royalty based sub-license agreement.
Reference
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AAV8
neutralization
AAV3
AAV7
AAV8
AAVrh10
dot blot
ICC-IF
neutralization
epitope mapping