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anti-Bombesin rabbit polyclonal, serum

Bombesin/GRP is widely distributed in the brain, in peripheral nerves and in endocrine cells of some mammalian species and birds. Bombesin/GRP occurs frequently in bronchial carcinoids.
Cat. No.: 16003
Quantity:  50 µL

Delivery Time: usually 1-7 working days

€303.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host rabbit
Antibody Type polyclonal
Immunogen Bombesin (#7113, Peninsula), conjugated to BSA
Purification undiluted antiserum
Conjugate unconjugated
Formulation lyophilized; reconstitute in 100 µl dist. water
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity chicken, human, rat

Applications

Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:800 - 1:3,000
Immunohistochemistry (IHC) - paraffin 1:800 - 1:3,000 (microwave treatment recommended)

Background

Details

Bombesin is an amphibian peptide and the mammalian counterpart is referred to as Gastrin Releasing Peptide (GRP). Bombesin/GRP is widely distributed in the brain, in peripheral nerves (particularly numerous in the gut) and in endocrine cells of some sub-mammalian species, e.g. in the oxyntic mucosa of birds. The peptide stimulates secretion from endocrine and exocrine cells and intestinal smooth muscle activity. Bombesin/GRP occurs frequently in the bronchial carcinoids.

Absorption with 10-100 µg bombesin and GRP per ml diluted antiserum abolishes the staining.

Positive control: Formalin-fixed paraffin and frozen sections of rat or chicken stomach.

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