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anti-Cdk7 mouse monoclonal, Mo-1.1, lyophilized, purified

The anti-Cdk7 monoclonal Mo-1.1 antibody reacts specifically with the 40 kD catalytic subunit (cdk7) of the cyclin-activating kinase (CAK), responsible for activation of cdks in G1, S and G2/M phases of the cell cycle; precipitates active kinase complex.
Cat. No.: 61063
Quantity:  50 µg

Delivery Time: usually 1-7 working days

$200.00
Excl. 19% Tax, excl. Shipping Cost

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Specifications

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG2b
Clone MO-1.1
Immunogen recombinant C-terminal 221 aa fragment of human wild-type cdk7/CAK (cyclin activating kinase)
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation lyophilized; reconstitute in 1 mL dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Intended use Research use only
Tested species reactivity human, mouse

Applications

Tested applications Tested dilutions
Flow Cytometry (FACS) assay dependent
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:10 - 1:20
Immunoprecipitation (IP) assay dependent
Western Blot (WB) assay dependent

Background

Details

Mo-1.1 recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase. The antibody is useful for cell cycle analysis, cell proliferation studies and for immunohistochemistry.

Reference

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