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anti-Cdk7 mouse monoclonal, Mo-1.1, supernatant

The anti-Cdk7 monoclonal Mo-1.1 antibody reacts specifically with the 40 kD catalytic subunit (Cdk7) of the CDK-activating kinase (CAK), responsible for phosphorylation of Cdks in G1, S and G2/M phases of the cell cycle; precipitates active kinase complex.
Cat. No.: 65163
Quantity:  5 mL

Delivery Time: usually 1-7 working days

€139.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG2b
Clone Mo-1.1
Immunogen recombinant C-terminal 221 aa fragment of human wildtype cdk7/CAK
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human, mouse

Applications

Tested applications Tested dilutions
Flow Cytometry (FACS) assay dependent
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen ready-to-use
Immunohistochemistry (IHC) - paraffin ready-to-use (microwave treatment recommended)
Immunoprecipitation (IP) assay dependent
Western Blot (WB) assay dependent

Background

Details

Mo-1.1 recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase. The antibody is useful for cell cycle analysis, cell proliferation studies and for immunohistochemistry.

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