anti-Chlamydia mouse monoclonal, ACI, lyophilized, purified, 500 µg

The anti-chlamydia antibody recognizes the genus-specific epitope of LPS antigen common to all chlamydia species.

Cat. No.: ACI-P500
Quantity: 500 µg

Delivery Time: usually 1-7 working days

$760.00

Excl. VAT, excl. Shipping Cost

Qty:

Publication

Species

Application

Borel, N. et al. Chlamydiae in human intestinal biopsy samples. Pathog.Dis. 76,- (2018).

human

IHC (paraffin)

Marti, H. et al. Evaluating the Antibiotic Susceptibility of Chlamydia - New Approaches for in Vitro Assays. Front.Microbiol. 9, 1414 (2018).

C. suis

ICC-IF

Staub, E. et al. Novel Chlamydia species isolated from snakes are temperature-sensitive and exhibit decreased susceptibility to azithromycin. Sci.Rep. 8, 5660 (2018).

C. pneumoniae

ICC-IF

Vidal, S. et al. Neglected zoonotic agents in cattle abortion: tackling the difficult to grow bacteria. BMC.Vet.Res. 13, 373 (2017).

C. abortus

IHC (paraffin)

Thierry, S. et al. Oral Uptake of Chlamydia psittaci by Ducklings Results in Systemic Dissemination. PLoS One 11, e015486 (2016).

C. psittaci

IHC (paraffin)

Leonard, C. A., Dewez, F. & Borel, N. Penicillin G-Induced Chlamydial Stress Response in a Porcine Strain of Chlamydia pecorum. Int. J. Microbiol. (2016). doi:10.1155/2016/3832917

C. pecorum

ICC-IF

Leonard, C. A., Schoborg, R. V & Borel, N. Damage/Danger Associated Molecular Patterns (DAMPs) Modulate Chlamydia pecorum and C. trachomatis Serovar E Inclusion Development In Vitro. PLoS One 10, e0134943 (2015).

C. trachomatis
C. pecorum

ICC-IF

Schoborg, R. V et al. Porcine epidemic diarrhea virus (PEDV) co-infection induced chlamydial persistence/stress does not require viral replication. Front. Cell. Infect. Microbiol. 4, (2014).

C. pecorum

ICC-IF

Marti, H., Koschwanez, M., Pesch, T., Blenn, C. & Borel, N. Water-Filtered Infrared A Irradiation in Combination with Visible Light Inhibits Acute Chlamydial Infection. PLoS One 9, (2014).

C. trachomatis
C. pecorum

ICC-IF

Borel, N. et al. Mixed infections with Chlamydia and porcine epidemic diarrhea virus - a new in vitro model of chlamydial persistence. BMC Microbiol. 10, (2010).

C. pecorum
C. abortus

ICC-IF

Borel, N. et al. Tissue microarray and immunohistochemistry as tools for evaluation of antibodies against Chlamydia-like bacteria. J. Med. Mirobiology 58, 863-866 (2009).

C. pneumoniae

IHC (paraffin)

Borel, N. et al. Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infection. BMC Infect. Dis. 6, (2006).

C. pneumoniae

ICC-IF

Soldati, G. et al. Detection of Mycobacteria and Chlamydiae in Granulomatous Inflammation of Reptiles: A Retrospective Study. Vet Pathol 41, 388-397 (2004).

C. spec

IHC (paraffin)

Alternative Products

Cat. No.	Product Name	Format	Quantity	Price
ACI-C	anti-Chlamydia mouse monoclonal, ACI	supernatant	1 mL	$84.00 Excl. VAT, excl. Shipping Cost
ACI-P	anti-Chlamydia mouse monoclonal, ACI	lyophilized, purified, 50 µg	50 µg	$166.00 Excl. VAT, excl. Shipping Cost

Product description

Host	mouse
Antibody Type	monoclonal
Isotype	IgG3
Clone	ACI
Immunogen	Chlamydia antigen
Purification	protein A affinity chromatography
Conjugate	unconjugated
Formulation	lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage	short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
Intended use	Research use only
Tested species reactivity	Chlamydia genus

Applications

Tested applications	Tested dilutions
ELISA	assay dependent
Immunocytochemistry (ICC)/ Immunofluorescence (IF)	1:100
Immunohistochemistry (IHC) - frozen	assay dependent

Background

Details

Mab ACI recognizes a genus-specific epitope of the Chlamydia lipopolysaccharide antigen and identifies all serovars (A-C, D-K, L1-L3) of C. trachomatis as well as Chlamydophila psittaci and Chlamydophila pneumoniae with a strong fluorescence of the intracellular inclusions, the pinhead-sized extracellular elementary bodies and the free cell-associated Chlamydia lipopolysaccharide anti-gens (amorphous foci).
A positive cross-reactivity was also reported for Chlamydophila pecorum.

Reference

Publication

Species

Application

Borel, N. et al. Chlamydiae in human intestinal biopsy samples. Pathog.Dis. 76,- (2018).

human

IHC (paraffin)

Marti, H. et al. Evaluating the Antibiotic Susceptibility of Chlamydia - New Approaches for in Vitro Assays. Front.Microbiol. 9, 1414 (2018).

C. suis

ICC-IF

Staub, E. et al. Novel Chlamydia species isolated from snakes are temperature-sensitive and exhibit decreased susceptibility to azithromycin. Sci.Rep. 8, 5660 (2018).

C. pneumoniae

ICC-IF

Vidal, S. et al. Neglected zoonotic agents in cattle abortion: tackling the difficult to grow bacteria. BMC.Vet.Res. 13, 373 (2017).

C. abortus

IHC (paraffin)

Thierry, S. et al. Oral Uptake of Chlamydia psittaci by Ducklings Results in Systemic Dissemination. PLoS One 11, e015486 (2016).

C. psittaci

IHC (paraffin)

Leonard, C. A., Dewez, F. & Borel, N. Penicillin G-Induced Chlamydial Stress Response in a Porcine Strain of Chlamydia pecorum. Int. J. Microbiol. (2016). doi:10.1155/2016/3832917

C. pecorum

ICC-IF

C. trachomatis
C. pecorum

ICC-IF

Schoborg, R. V et al. Porcine epidemic diarrhea virus (PEDV) co-infection induced chlamydial persistence/stress does not require viral replication. Front. Cell. Infect. Microbiol. 4, (2014).

C. pecorum

ICC-IF

Marti, H., Koschwanez, M., Pesch, T., Blenn, C. & Borel, N. Water-Filtered Infrared A Irradiation in Combination with Visible Light Inhibits Acute Chlamydial Infection. PLoS One 9, (2014).

C. trachomatis
C. pecorum

ICC-IF

Borel, N. et al. Mixed infections with Chlamydia and porcine epidemic diarrhea virus - a new in vitro model of chlamydial persistence. BMC Microbiol. 10, (2010).

C. pecorum
C. abortus

ICC-IF

Borel, N. et al. Tissue microarray and immunohistochemistry as tools for evaluation of antibodies against Chlamydia-like bacteria. J. Med. Mirobiology 58, 863-866 (2009).

C. pneumoniae

IHC (paraffin)

Borel, N. et al. Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infection. BMC Infect. Dis. 6, (2006).

C. pneumoniae

ICC-IF

Soldati, G. et al. Detection of Mycobacteria and Chlamydiae in Granulomatous Inflammation of Reptiles: A Retrospective Study. Vet Pathol 41, 388-397 (2004).

C. spec

IHC (paraffin)

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anti-Chlamydia mouse monoclonal, ACI, lyophilized, purified, 500 µg

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