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anti-Complement C1q mouse monoclonal, 242G3, lyophilized, purified

Detection of C1q in serum, in serum-C1 and within immune complexes. Useful for detection of C1q-bearing immune complexes in patients with rheumatic disorders.
Cat. No.: 610136
Quantity:  50 µg

Delivery Time: usually 1-7 working days

€196.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone 242G3
Immunogen purified human complement C1q
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation lyophilized; reconstitute in 1 mL dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
UniprotID P02745
Tested species reactivity human

Applications

Tested applications Tested dilutions
ELISA assay dependent
Western Blot (WB) 1:100

Background

Details

Detection of C1q in serum, in serum-C1 and within immune complexes; inhibits hemolytic activity of C1 by binding to C1q in the liquid phase (antibody concentration necessary to inhibit 50% of hemolytic activity in the fluid phase is 0.85 µg/ml). With C1 bound to immune complexes a dose dependent increase of C1 activity was observed at antibody concentrations of 1.5 µg/ml. Useful for detection of C1q-bearing immune complexes in patients with rheumatic disorders.

Polypeptide reacting: C-chain of complement C1q (25 kD in SDS-PAGE)

Reference

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