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anti-delta Catenin guinea pig polyclonal, serum

The anti-delta Catenin antibody reacts specifically with neurojungin (delta-catenin), a unique 140 kD polypeptide of the plakoglobin / armadillo protein family. Neurojungin is present in adhering type junctions in the nervous system and is primarily expressed in the brain.
Cat. No.: GP27
Quantity:  100 µL

Delivery Time: usually 1-7 working days

€266.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host guinea pig
Antibody Type polyclonal
Immunogen synthetic peptide J7 (corresponding to aa 1175-1192), coupled to KLH
Purification stabilized antiserum
Conjugate unconjugated
Formulation contains 0.09% sodium azide and 0.5% BSA
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity bovine, human, mouse, rat

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) 1:100
Immunohistochemistry (IHC) - frozen 1:100
Immunohistochemistry (IHC) - paraffin 1:100 (microwave treatment recommended)
Western Blot (WB) 1:2,500

Background

Details

The antibody reacts specifically with neurojungin (delta-catenin, a unique 160 kD polypeptide of the plakoglobin / armadillo protein family) present in adhering type junctions in the nervous system, primarily expressed in the brain. Delta-catenin also binds to presenilin-1, mutations of this protein are described to play a role in familial Alzheimer’s disease. No cross-reaction with other members of the armadillo / plakoglobin protein family.

Polypeptide reacting: Neurojungin (delta-catenin), 160 kD polypeptide.

Reactivity on cultured cell lines: Murine cell line A1B2, stably transfected with neurojungin cDNA.

Positive control: Murine brain, retina.

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