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anti-Desmin mouse monoclonal, D9, supernatant

The anti-desmin antibody is useful for the identification of myodifferentiation in tumors.
Cat. No.: 10519
Quantity:  1 mL

Delivery Time: usually 1-7 working days

€221.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone D9
Immunogen isolated from human leiomyoma
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human, mammals ((most mammals))

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:10 - 1:20
Immunohistochemistry (IHC) - paraffin 1:10 - 1:20 (microwave treatment recommended)
Western Blot (WB) assay dependent

Background

Details

Mab D9 specifically reacts with the cytoplasmic 53 kD desmin protein. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells.
The antibody can be used to distinguish rhabdomyosarcomas and leiomyosarcomas from other soft tissue tumors, lymphomas and carcinomas. Mab D9 does not crossreact with other intermediate filament proteins and is useful for the identification of myodifferentiation (also in tumors).
Positive control: Skeletal and smooth muscle myosarcomas

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