PROGEN - passion for research

close×

anti-Desmoglein 2 mouse monoclonal, 10G11, lyophilized, purified

The anti-desmoglein 2 antibody recognizes desmoglein 2 present in all epithelia, in heart muscle and lymphatic follicles.
Cat. No.: 61059
Quantity:  50 µg

Delivery Time: usually 1-7 working days

€201.00
Excl. 19% Tax, excl. Shipping Cost

Call us now for more information on our products: +49 6221 8278-0

Any more questions?
PRODUCT REQUEST

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone 10G11
Immunogen Recombinant peptide (220aa of 2nd and 3rd extracellular repeat domain)
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human ((negative with mouse and rat))

Applications

Tested applications Tested dilutions
ELISA assay dependent
Immunohistochemistry (IHC) - frozen 1:10 (For better resolution preincubation (directly after fixation) with 0.05 - 0.2% Triton X-100 for 5-10 min, depending on tissue type, is recommended (Schäfer S. et al., 1996))
Immunohistochemistry (IHC) - paraffin 1:10 (microwave treatment recommended)
Western Blot (WB) assay dependent

Background

Details

Antibody recognizes desmoglein 2 present in low concentrations in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles.
In basal epithelial cells desmoglein 2 expression is generally very low. Polypeptide reacting: desmoglein 2 (1069aa; calculated mol. wt. 116,760)
Reactivity on cultured cell lines: Many, including CaCo-2, HaCaT, MCF-7

Reference

Reference

PublicationSpeciesApplication
Biedermann, K. et al. Desmoglein 2 is expressed abnormally rather than mutated in familial and sporadic gastric cancer. J. Pathol. 207, 199–206 (2005). human IHC (paraffin)

Material safety data sheet

Please complete the form below to request a material safety data sheet

Personal Info

* Required Fields

Product Request

Personal Info

* Required Fields