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anti-Desmoglein 2 mouse monoclonal, 10G11, lyophilized, purified

The anti-desmoglein 2 antibody recognizes desmoglein 2 present in all epithelia, in heart muscle and lymphatic follicles.
Cat. No.: 61059
Quantity:  50 µg
No. of experiments:  ≤ 200 (IHC, 50 µl/slide)

Delivery Time: usually 1-7 working days

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone 10G11
Immunogen Recombinant peptide (220aa of 2nd and 3rd extracellular repeat domain)
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
No. of experiments ≤ 200 (IHC, 50 µl/slide)
Intended use Research use only
Tested species reactivity human (negative with mouse and rat)


Tested applications Tested dilutions
ELISA assay dependent
Immunohistochemistry (IHC) - frozen 1:10 (For better resolution preincubation (directly after fixation) with 0.05 - 0.2% Triton X-100 for 5-10 min, depending on tissue type, is recommended (Schäfer S. et al., 1996))
Western Blot (WB) assay dependent



Antibody recognizes desmoglein 2 present in low concentrations in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles.
In basal epithelial cells desmoglein 2 expression is generally very low. Polypeptide reacting: desmoglein 2 (1069aa; calculated mol. wt. 116,760)
Reactivity on cultured cell lines: Many, including CaCo-2, HaCaT, MCF-7


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