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anti-Desmoplakin 1/2 mouse monoclonal, DP I/II 236.23.1, supernatant

The anti-desmoplakin 1/2 antibody decorates desmoplakin 1 and 2 in desmosomal complexes. The anti-desmoplakin 1/2 antibody is useful for staining of primary and metastatic carcinoma.
Cat. No.: 651109
Quantity:  5 mL
No. of experiments:  ≤ 100 (IHC, 50 µl/slide)

Delivery Time: usually 1-7 working days

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG2b
Clone DP I/II 236.23.1
Immunogen C-terminal polypeptide of recombinant human desmoplakin (starting at amino acid position 1980)
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
No. of experiments ≤ 100 (IHC, 50 µl/slide)
Intended use Research use only
Tested species reactivity bovine, human, mouse


Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen ready-to-use
Immunohistochemistry (IHC) - paraffin ready-to-use (microwave treatment recommended)
Western Blot (WB) assay dependent



The antibody shows distinct punctate membrane staining of different epithelia. Desmosomes of the myocardium are also positive. Tumors specifically detected: Primary and metastatic carcinoma and meningioma. Polypeptides reacting: Desmoplakin 1 and 2 (Mr 250 000 and 215 000)

Reactivity on cultured cell lines: Several human carcinoma cell lines: MCF-7,A-431, HaCaT, CaCo2; bovine cells: MDBK, BMGE


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