Call +49 6221 8278-0

PROGEN - passion for research

close×

anti-Drebrin mouse monoclonal, MX823, ascites fluid

Specific for drebrin, a widespread actin-associating protein of 70 kD (SDS-PAGE mobility shows Mr 120,000), enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Positive staining was found in many tissues. Especially prominent in the mesangial cells of renal glomeruli and in the Sertoli cells of testis. Negative: hepatocytes and cross-striated muscle.
Cat. No.: 612128
Quantity:  250 µL
No. of experiments:  ≤ 500 (IHC, 50 µl/slide)

Delivery Time: usually 1-7 working days

$295.00
Excl. VAT, excl. Shipping Cost

Call us now for more information on our products: +49 6221 8278-0

Any more questions?
PRODUCT REQUEST

Specifications

Alternative Products

Cat. No. Product Name Format Quantity Price
651128

anti-Drebrin mouse monoclonal, MX823

supernatant 5 mL
$245.00
Excl. VAT, excl. Shipping Cost

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone MX823
Immunogen Synthetic c-terminal peptide (aa632-649) coupled to KLH
Purification ascites
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
No. of experiments ≤ 500 (IHC, 50 µl/slide)
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity bovine, dog, human, mouse, rat

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen at least 1:100
Immunoprecipitation (IP) assay dependent
Western Blot (WB) assay dependent

Background

Details

MX823 specifically reacts with drebrin, a widespread actin-associating protein of 70 kD (SDS-PAGE mobility shows Mr 120,000). It is enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Positive staining was found in many tissues, including diverse epithelia and  carcinoma (e.g. in epidermis basal cells are positive, whereas overlying cells are negative; also positive: regenerating epithelium during wound healing; basal cell carcinoma; skin melanoma), specific types of endothelia and smooth muscle; especially prominent in the mesangial cells of renal glomeruli and in the Sertoli cells of testis.
Also positive: epithelia of hair follicles and eccrine sweat glands. Consistently negative were, however, hepatocytes and cross-striated muscle.
Reactivity on cultured cell lines: Primary human keratinocytes, U333, MCF-7, SV80, B16 (mouse melanoma cells)

Reference

Material safety data sheet

Please complete the form below to request a material safety data sheet

Personal Info

* Required Fields

Product Request

Personal Info

* Required Fields