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anti-Factor VIIIc mouse monoclonal, MH104, lyophilized, purified

Mouse monoclonal anti- Factor VIIIc antibody.
Cat. No.: 610135
Quantity:  500 µg

Delivery Time: usually 1-7 working days

€414.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG2a
Clone MH104
Immunogen human factor VIII antigen
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human

Applications

Tested applications Tested dilutions
ELISA 1:5,000
Immunohistochemistry (IHC) - frozen assay dependent
Western Blot (WB) assay dependent

Background

Details

MH104 is specific for human factor VIIIc, a 300 kD protein present in plasma in a complex with von Willebrandt factor. Involved in the clotting cascade (activated by thrombin) by forming a complex with factor IXa, calcium, and phospholipids.

Polypeptide reacting: Factor VIIIc protein (epitope localization: intact 83 kD light chain).

Disorders specifically detected: Elevated levels of factor VIII have been associated with acute and chronic liver diseases, vascular disorders, diabetes and with acute-phase reactions.

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