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anti-Fibronectin mouse monoclonal, 568.0, supernatant

Marker to discriminate between small invasive carcinomas and benign proliferative lesions of the breast.
Cat. No.: 10707
Quantity:  1 mL

Delivery Time: usually 1-7 working days

€281.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone 568.0
Immunogen cultivated human fibroblasts
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.01% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) 1:5 - 1:10
Immunohistochemistry (IHC) - frozen 1:5 - 1:10
Immunohistochemistry (IHC) - paraffin 1:5 - 1:10 (microwave treatment recommended)
Western Blot (WB) assay dependent

Background

Details

Mab 568 reacts with the cell binding part of the fibronectin molecule. Fibronectin seems to play a key role in the tumor cell extracellular matrix during invasive tumor growth. Increasing expression of stromal fibronectin has been reported during tumor progression. In immunohistochemistry the antibody is reactive with an extracellular matrix glycoprotein in vessels and connective tissue.

Positive control: Human skin, ulcerating tissue

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