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anti-Hantavirus Puumala mouse monoclonal, A1C5, supernatant

The antibody is directed against the Puumala serotype nucleocapsid protein which has been shown to be the major immunogen in infections (HFRS, Nephropathia epidemica) caused by Puumala Virus.
Positive cross-reaction with Sin Nombra Virus (SNV).
No coss-reaction with Hantaan-related serogroups, like Dobrava, Seoul.
Cat. No.: A1C5-C
Quantity:  400 µL

Delivery Time: usually 1-7 working days

$141.00
Excl. 19% Tax, excl. Shipping Cost

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Specifications

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A1C5-POD

anti-Hantavirus Puumala POD mouse monoclonal, A1C5

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A1C5-P

anti-Hantavirus Puumala mouse monoclonal, A1C5

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone A1C5
Immunogen recombinant Puumala nucleocapsid protein
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity Puumala virus-infected cells

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:50
Western Blot (WB) assay dependent

Background

Details

A1C5 reacts with an epitope present on the N-terminus (between aa 15 and 35) of the nucleocapsid protein (S segment) of hantavirus CG 18-20 strain (Puumala serotype) and also cross-reacts with SNV (Sin Nombre virus) rN protein (Schmidt et al. 2005).

Schmidt, J., Meisel, H., Hjelle, B., Krüger, D. H. & Ulrich, R. Development and evaluation of serological assays for detection of human hantavirus infections caused by Sin Nombre virus. J. Clin. Virol. Off. Publ. Pan Am. Soc. Clin. Virol. 33, 247–53 (2005).

Reference

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