mouse tongue (courtesy of L. Langbein)

anti-Keratin K13 mouse monoclonal, Ks13.1, lyophilized, purified

The anti-keratin K13 Ks13.1 antibody reacts with non-cornified squamous epithelia and neoplasms derived therefrom. Protease pretreatment improves the performance of this excellent marker in immunohistochemistry.

Cat. No.: 61007
Quantity: 50 µg

Delivery Time: usually 1-7 working days

$251.00

Excl. 19% Tax, excl. Shipping Cost

Qty:

Publication

Species

Application

Heid, H. W., Moll, I. & Franke, W. W. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles. Differentiation. 37, 137â57 (1988).

human

IHC (frozen)

Heid, H. W., Moll, I. & Franke, W. W. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (h

human

IHC (frozen)

Moll, R. et al. Cytokeratins in normal and malignant transitional epithelium: maintenance of expression of urothelial differentiation features in transitional cell carcinomas and bladder carcinoma cell culture lines. Am. J. Pathol. 132, 123â144 (1988).

human

WB
IHC (frozen)
ICC-IF

Call us now for more information on our products: +49 6221 8278-0

Any more questions?
PRODUCT REQUEST

Learn more about the applications of our products

Specifications

Datasheet

Alternative Products

Cat. No.	Product Name	Format	Quantity	Price
65007	anti-Keratin K13 mouse monoclonal, Ks13.1	prediluted, purified, ready-to-use	5 mL	$161.00 Excl. 19% Tax, excl. Shipping Cost
19007	anti-Keratin K13 mouse monoclonal, Ks13.1	prediluted, purified	1 mL	$215.00 Excl. 19% Tax, excl. Shipping Cost

Product description

Host	mouse
Antibody Type	monoclonal
Isotype	IgG1
Clone	Ks13.1
Immunogen	Keratin K13 of Mr 54 000 purified from human esophagus
Purification	protein A affinity chromatography
Conjugate	unconjugated
Formulation	lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage	short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Intended use	Research use only
Tested species reactivity	bovine, human, rat

Applications

Tested applications	Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF)	assay dependent
Immunohistochemistry (IHC) - frozen	1:10
Immunohistochemistry (IHC) - paraffin	1:10 (protease treatment and/or microwave treatment recommended)
Western Blot (WB)	1:50 - 1:100

Background

Details

Ks 13.1 represents an excellent marker to discriminate non-cornified squamous epithelia from those of different origin.
Polypeptide reacting: Mr 54 000 polypeptide human keratin K13 (formerly designated cytokeratin13; with minor affinity to keratins K14, Mr 50 000, and K16, Mr 48 000 and also to K25, formerly designated K25irs1 from inner root sheath of hair follicle).
Tumors specifically detected: several squamous cell carcinomas, e.g. cervix carcinoma; transitional cell carcinoma of the bladder; craniopharyngioma
Reactivity on cultured cell lines: Cell lines from squamous cell CA, e.g. A-431 from epidermoid CA of vulva; RT 112, RT-4 of urinary bladder CA

Reference

Publication

Species

Application

Heid, H. W., Moll, I. & Franke, W. W. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles. Differentiation. 37, 137â57 (1988).

human

IHC (frozen)

human

IHC (frozen)

human

WB
IHC (frozen)
ICC-IF

Material safety data sheet

Please complete the form below to request a material safety data sheet

Personal Info

* Company / Institution

* Name
* Country

Phone
* E-mail address
* Privacy declaration
- By submitting the above request you agree that PROGEN stores and uses the data provided by you in accordance with the terms of use provided in the privacy declaration in order to process your request. You also agree that PROGEN may contact you with regard to your request or for marketing purposes (e.g. Mailchimp-Emailings). You can revoke your permission at any time without giving any reasons by sending an Email to info@progen.com or by writing to PROGEN at Maaßstraße 30, 69123 Heidelberg/Germany.

* Required Fields

Product Request

Personal Info

* Company / Institution

* Name
* Country

Phone
* E-mail address
* Ask your question
* Privacy declaration
- By submitting the above request you agree that PROGEN stores and uses the data provided by you in accordance with the terms of use provided in the privacy declaration in order to process your request. You also agree that PROGEN may contact you with regard to your request or for marketing purposes (e.g. Mailchimp-Emailings). You can revoke your permission at any time without giving any reasons by sending an Email to info@progen.com or by writing to PROGEN at Maaßstraße 30, 69123 Heidelberg/Germany.

* Required Fields

anti-Keratin K13 mouse monoclonal, Ks13.1, lyophilized, purified

Alternative Products