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mouse tongue (courtesy of L. Langbein)

anti-Keratin K13 mouse monoclonal, Ks13.1, prediluted, purified

The anti-keratin K13 Ks13.1 antibody reacts with non-cornified squamous epithelia and neoplasms derived therefrom. Protease pretreatment improves the performance of this excellent marker in immunohistochemistry.
Cat. No.: 19007
Quantity:  1 mL

Delivery Time: usually 1-7 working days

$215.00
Excl. 19% Tax, excl. Shipping Cost

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Specifications

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anti-Keratin K13 mouse monoclonal, Ks13.1

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65007

anti-Keratin K13 mouse monoclonal, Ks13.1

prediluted, purified, ready-to-use 5 mL
$161.00
Excl. 19% Tax, excl. Shipping Cost

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone Ks13.1
Immunogen Keratin K13 of Mr 54.000 purified from human esophagus
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation PBS with 0.5% BSA and 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Intended use Research use only
Tested species reactivity bovine, human, rat

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:50
Immunohistochemistry (IHC) - paraffin 1:50 (microwave treatment recommended)
Western Blot (WB) assay dependent

Background

Details

Ks 13.1 represents an excellent marker to discriminate non-cornified squamous epithelia from those of different origin. Polypeptide reacting: Mr 54 000 polypeptide (human cytokeratin13 with minor affinity to cytokeratins 14, Mr 50 000, and 16, Mr 48 000. Tumors specifically detected: several squamous cell carcinomas, e.g. cervix carcinoma; transitional cell carcinoma of the bladder; craniopharyngioma.

Positive control: Cell lines (tested so far) from squamous cell CA, e.g. A-431 from epidermoid CA of vulva; RT 112, RT-4 of urinary bladder CA.

Reference

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