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anti-Keratin K17 mouse monoclonal, Ks17.E3, supernatant

The antibody recognizes myoepithelial cells; benign tumors of mammary gland; malignant forms are negative.
Cat. No.: 65136
Quantity:  5 mL

Delivery Time: usually 1-7 working days

€139.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG2b
Clone Ks17.E3
Immunogen Human keratin K17 of Mr 46,000
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human, rat

Applications

Immunocytochemistry (ICC)/ Immunofluorescence (IF) ready-to-use
Immunohistochemistry (IHC) - frozen ready-to-use
Immunohistochemistry (IHC) - paraffin ready-to-use (microwave treatment recommended)
Western Blot (WB) assay dependent

Background

Details

Ks 17.E3 represents an excellent marker to distinguish myoepithelial cells (positive for K17) from luminal epithelium of various glands (mammary, sweat, salivary, bronchial, tracheal, laryngeal, esophageal) and benign from malignant forms of e.g. mammary gland tumors. In the epidermis suprabasal staining is found only in cornifying regions and in the outer root sheath of hair follicles.

Reactivity on cultured cell lines: HeLa, A-431  

Tumors specifically detected: Benign tumors of mammary gland; most malignant forms of mammary tumors are negative for keratin K17

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