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anti-Keratin K19 mouse monoclonal, Ks19.10, supernatant

Ks19.10 represents an excellent marker to discriminate glandular epithelial carcinoma from those of different origin. No reaction with hepatocellular carcinoma.
Cat. No.: 65135
Quantity:  5 mL

Delivery Time: usually 1-7 working days

$191.00
Excl. 19% Tax, excl. Shipping Cost

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Specifications

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone Ks19.10
Immunogen Cytoskeletal preparation from human tumor cell line MCF-7
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Intended use Research use only
Tested species reactivity bovine, human, rat

Applications

Tested applications Tested dilutions
ELISA assay dependent
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen ready-to-use
Western Blot (WB) assay dependent

Background

Details

Ks 19.10 represents a sensitive marker to discriminate glandular epithelia (and tumors derived therefrom) from those of different origin.
No reaction with hepatocellular CA!
Tumors specifically detected: All adeno-CA tested; cholangio CA of liver; renal cell CA, transitional cell CA of bladder; ovary CA; squamous cell CA of cervix, bronchus and lung (intermediate type); carcinoid tumor of bronchus; mammary CA.
Polypeptide reacting: Mr 40 000 polypeptide (keratin K19; formerly also designated cytokeratin 19) of human glandular epithelia.
Reactivity on cultured cell lines: MCF-7, negative on PLC.

Reference

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