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anti-Keratin K19 mouse monoclonal, Ks19.2 (Z105.6), supernatant

Ks19.2 represents an excellent marker to discriminate glandular epithelial carcinoma from those of different origin. No reaction with hepatocellular carcinoma.
Cat. No.: 65129
Quantity:  5 mL

Delivery Time: usually 1-7 working days

€139.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG2b
Clone Ks19.2 (Z105.6)
Immunogen Keratin K19 of Mr 40 000; from cultured human MCF-7 cells
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity bovine, fish, human, rabbit, rat ((not with mouse, woodchuck, chicken, xenopus))

Applications

Tested applications Tested dilutions
ELISA assay dependent
Immunohistochemistry (IHC) - frozen ready-to-use
Western Blot (WB) assay dependent

Background

Details

Ks 19.2 represents an excellent marker to discriminate glandular epithelial CA from those of different origin. No reaction with hepatocellular CA!
Tumors specifically detected: All tested adeno CA; cholangio CA of liver; renal cell CA; transitional cell CA of the bladder; ovary CA; squamous cell CA of cervix, bronchus and lung (intermediate type); mesothelioma; carcinoid tumor of bronchus; breast CA; thymoma.
Polypeptide reacting: Mr 40 000 polypeptide (keratin K19; formerly also designated cytokeratin 19) of human glandular epithelia. The epitope has been localized on aa. 352-368 (VRADSERQNQEYQRLMD) of the α-helical fragment.
Reactivity on cultured cell lines: MCF-7, RT 112, Detroit 562, RPMI 2650, HT-29, SSC-12

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