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anti-Keratin K2 mouse monoclonal, Ks2.398.3.1, supernatant

The antibody is reactive with epidermal cells in uppermost suprabasal layers incl. scalp, foot and sole. No reaction with palate keratin 76.
Cat. No.: 65177
Quantity:  1 mL

Delivery Time: usually 1-7 working days

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone Ks2.398.3.1
Immunogen synthetic peptide (N-terminal amino acids nos. 2-23) of human keratin K2 (MW 65,852)
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human ( negative with bovine, mouse, rat, Xenopus laevis)
Intended use Research use only


Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:150
Immunohistochemistry (IHC) - paraffin 1:150 (microwave treatment recommended)
Western Blot (WB) assay dependent



Ks2.398.3.1 represents an excellent marker to study terminal epidermal differentiation. The mab is reactive with epidermal cells in uppermost supra­basal layers including scalp, foot and sole. It recognizes individual cells within epidermis of tongue and mamille (co-localization with keratin K10). It is also reactive on hyperkeratosis of diverse viral and genetic origin.

The mab does not react with palate keratin K76.

Reactive polypeptide: Basic human keratin K2 (MW 65,852; formerly also designated cytokeratin 2e).

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