Call +49 6221 8278-0

PROGEN - passion for research

close×

anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22, FITC Conjugate

Decorates all epithelia and epithelium-derived neoplasms. C22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors.
Cat. No.: 61431
Quantity:  250 µL

Delivery Time: usually 1-7 working days

$377.00
Excl. 19% Tax, excl. Shipping Cost

Call us now for more information on our products: +49 6221 8278-0

Any more questions?
PRODUCT REQUEST

Specifications

Alternative Products

Cat. No. Product Name Format Quantity Price
61531

anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22

Biotin Conjugate 250 µL
$377.00
Excl. 19% Tax, excl. Shipping Cost
65031

anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22

prediluted, purified 5 mL
$220.00
Excl. 19% Tax, excl. Shipping Cost
61031

anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22

lyophilized, purified 50 µg
$289.00
Excl. 19% Tax, excl. Shipping Cost
690031

anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22

liquid, purified 1 mL (50 µg/mL)
$425.00
Excl. 19% Tax, excl. Shipping Cost
690031S

anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22

liquid, purified, small 0.2 mL (50 µg/mL)
$170.00
Excl. 19% Tax, excl. Shipping Cost

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone Ks 5+8.22/C22
Immunogen human keratin K8, purified from SDS PAGE gel
Purification protein A affinity chromatography
Conjugate FITC
Formulation contains 0.09% sodium azide
Storage store at 2 – 8 °C
UniprotID P05787
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity amphibia, bovine, human, hydra, mouse, pig

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:10
Immunohistochemistry (IHC) - paraffin 1:10 (protease treatment and microwave treatment recommended)

Background

Details

C 22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors. The antibody specifically reacts with keratins K5 and K8 present in nearly all epithelia. Polypeptide reacting: Mr 52 500, Mr 58 000 keratins (type II keratins K5 and K8; formerly also designated cytokeratins 5 and 8) of human epithelial cells. Epitope has been mapped to aa 353-367 on alpha helical rod domain of Keratin K8 (Waseeman et al. 2004)

Tested cultured cell lines: MCF-7, RT 112, HT-29, Detroit 562, RPMI 2650, SSC-12, bovine BMGE+H, BMGE-H, MDBK



Waseem, A. et al. Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability. Biochemistry 43, 1283–95 (2004).

Reference

There are currently no references for this product.

Material safety data sheet

Please complete the form below to request a material safety data sheet

Personal Info

* Required Fields

Product Request

Personal Info

* Required Fields