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anti-Keratin K6 (C-terminus) guinea pig polyclonal, serum

MW 56,000 intermediate filament polypeptide, keratin K6, detected by immunohistochemistry in non-keratinized squamous epithelia and proliferating cells of epidermis (e.g. within psoriatic lesions).
Cat. No.: GP91
Quantity:  100 µL

Delivery Time: usually 1-7 working days

€249.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host guinea pig
Antibody Type polyclonal
Immunogen Synthetic peptide of human keratin K6 (C-SSTIKYTTTSS), coupled to KLH
Purification stabilized antiserum
Conjugate unconjugated
Formulation contains 0.09% sodium azide and 0.5% BSA
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human, mouse

Applications

Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - paraffin 1:100 - 1:200 (microwave treatment recommended)

Background

Details

In immunohistochemistry, the antibody detects keratin K6 in non-keratinized squamous epithelia, follicular outer root sheath and proliferating cells of epidermis (e.g. within psoriatic lesions). It is completely negative on non-stratified epithelia. Suitable for discrimination of keratinizing and non-keratinizing squamous cell carcinoma versus e.g. poorly differentiated adenocarcinoma.

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