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human uvula (courtesy of J.Heß, University Hospital Heidelberg) Zoom

human uvula (courtesy of J.Heß, University Hospital Heidelberg)

anti-Keratin K6 (C-terminus) guinea pig polyclonal, serum

MW 56,000 intermediate filament polypeptide, keratin K6, detected by immunohistochemistry in non-keratinized squamous epithelia and proliferating cells of epidermis (e.g. within psoriatic lesions).
Cat. No.: GP91
Quantity:  100 µL
No. of experiments:  ≤ 400 (IHC, 50 µl/slide)

Delivery Time: usually 1-7 working days

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Product description

Host guinea pig
Antibody Type polyclonal
Immunogen Synthetic peptide of human keratin K6 (C-SSTIKYTTTSS), coupled to KLH
Purification stabilized antiserum
Conjugate unconjugated
Formulation contains 0.09% sodium azide and 0.5% BSA
Storage short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
No. of experiments ≤ 400 (IHC, 50 µl/slide)
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity human, mouse


Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:100 - 1:200
Immunohistochemistry (IHC) - paraffin 1:100 - 1:200 (microwave treatment recommended)



In immunohistochemistry, the antibody detects keratin K6 in non-keratinized squamous epithelia, follicular outer root sheath and proliferating cells of epidermis (e.g. within psoriatic lesions). It is completely negative on non-stratified epithelia.
Suitable for discrimination of keratinizing and non-keratinizing squamous cell carcinoma versus e.g. poorly differentiated adenocarcinoma.

Reactive polypeptide: Human type II (basic) keratin K6 (formerly also designated cytokeratin 6); MW 56,000 (pI 7.8).

Positive control: Human psoriatic skin; rete ridges of foot sole.


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