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anti-LDL Receptor rabbit polyclonal, Biotin Conjugate

The antibody to LDL-R reacts specifically with human LDL-R and is suitable for use in flow cytometry and Immunoblotting. Antibody does not seem to inhibit binding of LDL.
Cat. No.: 61599
Quantity:  250 µL

Delivery Time: usually 1-7 working days

$391.00
Excl. VAT, excl. Shipping Cost

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Specifications

Alternative Products

Cat. No. Product Name Format Quantity Price
61099

anti-LDL Receptor rabbit polyclonal

serum 250 µL (0.1 mg/mL)
$305.00
Excl. VAT, excl. Shipping Cost

Product description

Host rabbit
Antibody Type polyclonal
Isotype IgG
Immunogen Specific synthetic peptide (sequence not conserved in VLDL receptor and LRP) of the LDL receptor extracellular domain (epitope between residues nos. 184-195, the linker region between repeats 4 and 5)
Purification protein A affinity chromatography
Conjugate biotin
Formulation PBS pH 7.4 with penicillin/ streptomycin
Storage store at 2-8°C
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity human

Applications

Tested applications Tested dilutions
Flow Cytometry (FACS) 1:10
Receptor Binding Assays assay dependent

Background

Details

The LDL receptor (160 kD mature or glycosylated receptor; 120 kD precursor or unglycosylated receptor) plays a key role in cellular cholesterol homeostasis.
The antibody to LDL-R reacts specifically with human LDL-R and is suitable for use in flow cytometry and immuno-blotting. First data show that the antibody does not inhibit binding of LDL. In immunoblotting, the antibody recog¬nizes the 160 kD band of LDLR and a 120 kD band of the LDLR precursor from fibroblasts, hepatocytes, and monocytic cells cultured in the presence of lipoprotein-deficient serum.

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