Call +49 6221 8278-0

PROGEN - passion for research

close×

anti-LRP1 (515kD) mouse monoclonal, 8G1, lyophilized w/o sodium azide, purified

The antibody recognizes human 515 kD alpha chain of the low density lipoprotein receptor-related protein. Useful marker for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD91).

Cat. No.: 61065
Quantity:  50 µg

Delivery Time: usually 1-7 working days

$293.00
Excl. 19% Tax, excl. Shipping Cost

Call us now for more information on our products: +49 6221 8278-0

Any more questions?
PRODUCT REQUEST

Specifications

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone 8G1
Immunogen human LRP/alpha2MR
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation lyophilized; reconstitute in 1 mL dist. water (final solution contains 0.5% BSA in PBS buffer, pH 7.4)
Storage short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
Intended use Research use only
Tested species reactivity human

Applications

Tested applications Tested dilutions
Flow Cytometry (FACS) assay dependent
Immunohistochemistry (IHC) - frozen 1:20
Immunohistochemistry (IHC) - paraffin 1:20 (microwave treatment recommended)
Western Blot (WB) assay dependent

Background

Details

8G1 specifically reacts with the 515 kDa a-chain of human LRP/a2MR which is expressed in a restricted spectrum of cell types (Herz & Strickland, 2001). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD 91).

Herz J and Strickland DK: LRP, a multifunctional scavanger and signaling receptor. J. Clin. Invest. 108, 779-784 (2001).

Reference

Material safety data sheet

Please complete the form below to request a material safety data sheet

Personal Info

* Required Fields

Product Request

Personal Info

* Required Fields