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  • anti-Nephrin guinea pig polyclonal, serum

mouse kidney (courtesy of J.Heß, University Hospital Heidelberg) Zoom

mouse kidney (courtesy of J.Heß, University Hospital Heidelberg)

anti-Nephrin guinea pig polyclonal, serum

The anti-nephrin antibody reacts specifically with nephrin, first described as a kidney podocyte marker protein, and stains positively podocytes of the kidney, radial glial cells of the brain, Sertoli cells of testis, and beta islet cells of the pancreas. Directed against the intracellular domain.

highly_published external_validation
Cat. No.: GP-N2
Quantity:  100 µL

Delivery Time: usually 1-7 working days

$312.00
Excl. 19% Tax, excl. Shipping Cost

Filter

Publication
Species
Application
Brinkkoetter, P. et al. Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics. Cell.Rep. 27, 1551-1566.e5 (2019)
mouse
IHC-IF (paraffin)
Kurihara, Y. et al. Chlamydia trachomatis targets mitochondrial dynamics to promote intracellular survival and proliferation. Cell.Microbiol. 21, e12962 (2019)
C. trachomatis
ICC-IF
Neutzner, A. et al. A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct. Fluids.Barriers.CNS. 16, 17 (2019)
human
IHC (paraffin)
Tanigawa, S. et al. Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes. Stem.Cell.Reports. 11, 727-740 (2018).
human
IHC-IF (frozen)
Lenoir, O. et al. Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries. J.Diabetes.Res. 2017, 9603924 (2018).
mouse
IHC (paraffin)
Artelt, N. et al. Comparative Analysis of Podocyte Foot Process Morphology in Three Species by 3D Super-Resolution Microscopy. Front.Med.(Lausanne). 5, 292 (2018).
human
mouse
rat
IHC (paraffin)
Maeda, K. et al. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. J.Clin.Invest. 128, 3445-3459 (2018).
mouse
FACS
Dorotea, D. et al. Orally active, species-independent novel A3 adenosine receptor antagonist protects against kidney injury in db/db mice. Exp.Mol.Med. 50, 38 (2018).
mouse
IHC (paraffin)
Rauch, C. et al. Differentiation of human iPSCs into functional podocytes. PLoS.One. 13, e0203869 (2018).
human
WB
Luo, W. et al. Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy. Front.Immunol. 9, 1433 (2018).
mouse
IHC-IF (frozen)
Siegerist, F. et al. Novel Microscopic Techniques for Podocyte Research. Front.Endocrinol.(Lausanne). 9, 379 (2018).
mouse
rat
IHC-IF (paraffin)
Ruhnke, L. et al. Progenitor Renin Lineage Cells are not involved in the regeneration of glomerular endothelial cells during experimental renal thrombotic microangiopathy. PLoS.One. 13, e0196752 (2018).
mouse
IHC-IF (paraffin)
Uchida, T. et al. Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice. Sci.Rep. 8, 8225 (2018).
mouse
IHC-IF (paraffin)
Ma, Y. et al. Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II. Cell.Death.Dis. 9, 185 (2018).
grivet monkey
WB
Cabe, M. et al. PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation. Biochem.Biophys.Res.Commun. 503, 2306-2311 (2018)
mouse
WB
Krchňáková, Z. et al. Splicing of long non-coding RNAs primarily depends on polypyrimidine tract and 5' splice-site sequences due to weak interactions with SR proteins. Nucleic.Acids.Res. , (2018)
human
WB
Whytock, K. et al. Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise. J.Physiol. 596, 2077-2090 (2018)
human
IHC-IF (frozen)
Kliewe, F. et al. Studying the role of fascin-1 in mechanically stressed podocytes. Sci.Rep. 7, 9916 (2017).
human
mouse
IHC-IF (paraffin)
Siegerist, F. et al. Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement. Sci.Rep. 7, 11473 (2017).
human
IHC-IF (paraffin)
Dumont, V. et al. PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease. FASEB.J. 31, 3978-3990 (2017).
human
mouse
WB
Musah, S. et al. Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. Nat.Biomed.Eng. 1,- (2017).
human
ICC-IF
Henique, C. et al. Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis. Nat.Commun. 8, 1829 (2017).
human
mouse
IHC-IF (paraffin)
Lin, J. et al. ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics. PLoS.One. 12, e0184575 (2017).
human
IHC-IF (paraffin)
Kwon, G. et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 8, 74217-74232 (2017).
mouse
IHC (paraffin)
Kravic, B. et al. In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy. 14, 311-335 (2017)
mouse
IHC (frozen)
Vasilopoulou, E. et al. Loss of endogenous thymosin ?4 accelerates glomerular disease. Kidney Int. 90, 1056-1070 (2016).
mouse
IHC (paraffin)
Sharmin, S. et al. Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation. J. Am. Soc. Nephrol. 27, 1778-1791 (2016).
human
IHC
ICC-IF
FACS
Königshausen, E. et al. Angiotensin II increases glomerular permeability by ?-arrestin mediated nephrin endocytosis. Nat. Publ. Gr. 6, (2016).
mouse
WB
IHC (paraffin)
IP
Gödel, M. et al. Microtubule Associated Protein 1b (MAP1B) Is a Marker of the Microtubular Cytoskeleton in Podocytes but Is Not Essential for the Function of the Kidney Filtration Barrier in Mice. PLoS One 10, (2015).
rat
IHC (frozen)
Denhez, B. et al. Increased SHP-1 Protein Expression by High Glucose Levels Reduces Nephrin Phosphorylation in Podocytes. J. Biol. Chem. -290, 350-359 (2015).
mouse
IHC (paraffin)
Hyvönen, M. E. et al. Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy. Biomed Res. Int. 2015, (2015).
mouse
IHC (frozen)
Schell, C. et al. Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response. PLoS One 10, e0129424 (2015).
mouse
IHC (frozen)
Schulte, K. et al. Origin of parietal podocytes in atubular glomeruli mapped by lineage tracing. J. Am. Soc. Nephrol. 25, 129-41 (2014).
mouse
IHC (frozen)
Ihara, K. I. et al. MAGI-2 is critical for the formation and maintenance of the glomerular filtration barrier in mouse kidney. Am. J. Pathol. 184, 2699-2708 (2014).
mouse
IHC (frozen)
IEM
Boerries, M. et al. Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Kidney Int. 83, 1052-1064 (2013).
mouse
WB
Bechtel, W. et al. Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis. J. Am. Soc. Nephrol. 24, 727-43 (2013).
mouse
IHC (paraffin)
Hartleben, B. et al. aPKC?/? and aPKC? contribute to podocyte differentiation and glomerular maturation. J. Am. Soc. Nephrol. 24, 253-67 (2013).
mouse
IHC (frozen)
Shimizu, A. et al. ARB protects podocytes from HIV-1 nephropathy independently of podocyte AT1. Nephrol. Dial. Transplant. 27, 3169-3175 (2012).
mouse
IHC (paraffin)
Haege, S. et al. CXC Chemokine Receptor 7 (CXCR7) Regulates CXCR4 Protein Expression and Capillary Tuft Development in Mouse Kidney. PLoS One 7, (2012).
mouse
IHC (paraffin)
Hartleben, B. et al. Role of the Polarity Protein Scribble for Podocyte Differentiation and Maintenance. PLoS One 7, (2012).
mouse
IHC (frozen)
Niethamer, T. K. et al. Oral monosaccharide therapies to reverse renal and muscle hyposialylation in a mouse model of GNE myopathy. Mol. Genet. Metab. -107, 748-755 (2012).
mouse
WB
Kakani, S. et al. The Gne M712T Mouse as a Model for Human Glomerulopathy. Am. J. Pathol. 180, 1431-1440 (2012).
mouse
WB
Wagner, N. et al. The podocyte protein nephrin is required for cardiac vessel formation. Hum. Mol. Genet. 20, 2182-2194 (2011).
mouse
IHC (frozen)
IHC (paraffin)
Gödel, M. et al. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J. Clin. Invest. 121, 2197-2209 (2011).
mouse
IHC (frozen)
Inoki, K. et al. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J. Clin. Invest. 121, 2181-2196 (2011).
human
IHC (frozen)
Puliti, A. et al. Albuminuria and Glomerular Damage in Mice Lacking the Metabotropic Glutamate Receptor 1. Am. J. Pathol. 178, 1257-1269 (2011).
mouse
WB
IHC (frozen)
ICC-IF
Matsusaka, T. et al. Podocyte injury damages other podocytes. J. Am. Soc. Nephrol. 22, 1275-85 (2011).
mouse
IHC (paraffin)
Matsusaka, T. et al. Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection. Am. J. Physiol. - Ren. Physiol. 300, F792-800 (2011).
mouse
WB
IHC (paraffin)
Meyer-Schwesinger, C. et al. Nephrotic Syndrome and Subepithelial Deposits in a Mouse Model of Immune-Mediated Anti-Podocyte Glomerulonephritis. J. Immunol. 187, 3218-3229 (2011).
mouse
IHC (paraffin)
Matsusaka, T. et al. ARB Protection Against Podocyte-Induced Sclerosis is Podocyte AT1-Independent. Hypertension 55, 967-973 (2010).
mouse
IHC (paraffin)
Li, Y. et al. Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis. J. Am. Soc. Nephrol. 20, 1907-18 (2009).
mouse
WB
IHC (frozen)
Turk, T. et al. BMP Signaling and Podocyte Markers Are Decreased in Human Diabetic Nephropathy in Association With CTGF Overexpression. J. Histochem. Cytochem. 57, 623-631 (2009).
human
IHC (paraffin)
Takabatake, Y. et al. The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature. J. Am. Soc. Nephrol. 20, 1714-23 (2009).
mouse
IHC (frozen)
Collino, F. et al. Preeclamptic sera induce nephrin shedding from podocytes through endothelin-1 release by endothelial glomerular cells. Am. J. Physiol. - Ren. Physiol. 294, 1185-1194 (2008).
human
WB
ICC-IF
Favaro, E. et al. Hyperglycemia Induces Apoptosis of Human Pancreatic Islet Endothelial Cells Effects of Pravastatin on the Akt Survival Pathway. Am. J. Pathol. 173, 442-450 (2008).
human
WB
IP
Uchida, K. et al. Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis. Kidney Int. 73, 926-932 (2008).
human
IHC
Wagner, K.-D. et al. Report An Inducible Mouse Model for PAX2-Dependent Glomerular Disease: Insights into a Complex Pathogenesis. Curr. Biol. 16, 793-800 (2006).
human
IHC
Bussolati, B. et al. Statins Prevent Oxidized LDL-Induced Injury of Glomerular Podocytes by Activating the Phosphatidylinositol 3-Kinase/ AKT-Signaling Pathway. J. Am. Soc. Nephrol.- JASN -16, 1936-1947 (2005).
human
ICC-IF

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Specifications

Product description

Host guinea pig
Antibody Type polyclonal
Immunogen Synthetic peptide of mouse Nephrin (intracellular domain, aa1243-1256, EPGSLPFELRGHLV)
Purification stabilized antiserum
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity human, mouse

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:50
Immunohistochemistry (IHC) - paraffin 1:50 (microwave treatment recommended)
Western Blot (WB) 1:500

Background

Details

The antibody reacts specifically with nephrin, first described as a kidney podocyte marker protein (MW 135,000 calculated from aa sequence data; apparent Mr 185,000 after SDS-PAGE).
Nephrin is a transmembrane cell adhesion molecule located at the slit diaphragm.
Immunolocalization: The antibody stains positively podocytes of the kidney, radial glial cells of the brain, Sertoli cells of testis, and beta islet cells of the pancreas.
Tested cultured cell lines: PCL (podocyte cell line), M-1 (cortical collecting duct cells)

Reference

Filter

Publication
Species
Application
Brinkkoetter, P. et al. Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics. Cell.Rep. 27, 1551-1566.e5 (2019)
mouse
IHC-IF (paraffin)
Kurihara, Y. et al. Chlamydia trachomatis targets mitochondrial dynamics to promote intracellular survival and proliferation. Cell.Microbiol. 21, e12962 (2019)
C. trachomatis
ICC-IF
Neutzner, A. et al. A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct. Fluids.Barriers.CNS. 16, 17 (2019)
human
IHC (paraffin)
Tanigawa, S. et al. Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes. Stem.Cell.Reports. 11, 727-740 (2018).
human
IHC-IF (frozen)
Lenoir, O. et al. Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries. J.Diabetes.Res. 2017, 9603924 (2018).
mouse
IHC (paraffin)
Artelt, N. et al. Comparative Analysis of Podocyte Foot Process Morphology in Three Species by 3D Super-Resolution Microscopy. Front.Med.(Lausanne). 5, 292 (2018).
human
mouse
rat
IHC (paraffin)
Maeda, K. et al. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. J.Clin.Invest. 128, 3445-3459 (2018).
mouse
FACS
Dorotea, D. et al. Orally active, species-independent novel A3 adenosine receptor antagonist protects against kidney injury in db/db mice. Exp.Mol.Med. 50, 38 (2018).
mouse
IHC (paraffin)
Rauch, C. et al. Differentiation of human iPSCs into functional podocytes. PLoS.One. 13, e0203869 (2018).
human
WB
Luo, W. et al. Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy. Front.Immunol. 9, 1433 (2018).
mouse
IHC-IF (frozen)
Siegerist, F. et al. Novel Microscopic Techniques for Podocyte Research. Front.Endocrinol.(Lausanne). 9, 379 (2018).
mouse
rat
IHC-IF (paraffin)
Ruhnke, L. et al. Progenitor Renin Lineage Cells are not involved in the regeneration of glomerular endothelial cells during experimental renal thrombotic microangiopathy. PLoS.One. 13, e0196752 (2018).
mouse
IHC-IF (paraffin)
Uchida, T. et al. Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice. Sci.Rep. 8, 8225 (2018).
mouse
IHC-IF (paraffin)
Ma, Y. et al. Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II. Cell.Death.Dis. 9, 185 (2018).
grivet monkey
WB
Cabe, M. et al. PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation. Biochem.Biophys.Res.Commun. 503, 2306-2311 (2018)
mouse
WB
Krchňáková, Z. et al. Splicing of long non-coding RNAs primarily depends on polypyrimidine tract and 5' splice-site sequences due to weak interactions with SR proteins. Nucleic.Acids.Res. , (2018)
human
WB
Whytock, K. et al. Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise. J.Physiol. 596, 2077-2090 (2018)
human
IHC-IF (frozen)
Kliewe, F. et al. Studying the role of fascin-1 in mechanically stressed podocytes. Sci.Rep. 7, 9916 (2017).
human
mouse
IHC-IF (paraffin)
Siegerist, F. et al. Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement. Sci.Rep. 7, 11473 (2017).
human
IHC-IF (paraffin)
Dumont, V. et al. PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease. FASEB.J. 31, 3978-3990 (2017).
human
mouse
WB
Musah, S. et al. Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. Nat.Biomed.Eng. 1,- (2017).
human
ICC-IF
Henique, C. et al. Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis. Nat.Commun. 8, 1829 (2017).
human
mouse
IHC-IF (paraffin)
Lin, J. et al. ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics. PLoS.One. 12, e0184575 (2017).
human
IHC-IF (paraffin)
Kwon, G. et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 8, 74217-74232 (2017).
mouse
IHC (paraffin)
Kravic, B. et al. In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy. 14, 311-335 (2017)
mouse
IHC (frozen)
Vasilopoulou, E. et al. Loss of endogenous thymosin ?4 accelerates glomerular disease. Kidney Int. 90, 1056-1070 (2016).
mouse
IHC (paraffin)
Sharmin, S. et al. Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation. J. Am. Soc. Nephrol. 27, 1778-1791 (2016).
human
IHC
ICC-IF
FACS
Königshausen, E. et al. Angiotensin II increases glomerular permeability by ?-arrestin mediated nephrin endocytosis. Nat. Publ. Gr. 6, (2016).
mouse
WB
IHC (paraffin)
IP
Gödel, M. et al. Microtubule Associated Protein 1b (MAP1B) Is a Marker of the Microtubular Cytoskeleton in Podocytes but Is Not Essential for the Function of the Kidney Filtration Barrier in Mice. PLoS One 10, (2015).
rat
IHC (frozen)
Denhez, B. et al. Increased SHP-1 Protein Expression by High Glucose Levels Reduces Nephrin Phosphorylation in Podocytes. J. Biol. Chem. -290, 350-359 (2015).
mouse
IHC (paraffin)
Hyvönen, M. E. et al. Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy. Biomed Res. Int. 2015, (2015).
mouse
IHC (frozen)
Schell, C. et al. Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response. PLoS One 10, e0129424 (2015).
mouse
IHC (frozen)
Schulte, K. et al. Origin of parietal podocytes in atubular glomeruli mapped by lineage tracing. J. Am. Soc. Nephrol. 25, 129-41 (2014).
mouse
IHC (frozen)
Ihara, K. I. et al. MAGI-2 is critical for the formation and maintenance of the glomerular filtration barrier in mouse kidney. Am. J. Pathol. 184, 2699-2708 (2014).
mouse
IHC (frozen)
IEM
Boerries, M. et al. Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Kidney Int. 83, 1052-1064 (2013).
mouse
WB
Bechtel, W. et al. Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis. J. Am. Soc. Nephrol. 24, 727-43 (2013).
mouse
IHC (paraffin)
Hartleben, B. et al. aPKC?/? and aPKC? contribute to podocyte differentiation and glomerular maturation. J. Am. Soc. Nephrol. 24, 253-67 (2013).
mouse
IHC (frozen)
Shimizu, A. et al. ARB protects podocytes from HIV-1 nephropathy independently of podocyte AT1. Nephrol. Dial. Transplant. 27, 3169-3175 (2012).
mouse
IHC (paraffin)
Haege, S. et al. CXC Chemokine Receptor 7 (CXCR7) Regulates CXCR4 Protein Expression and Capillary Tuft Development in Mouse Kidney. PLoS One 7, (2012).
mouse
IHC (paraffin)
Hartleben, B. et al. Role of the Polarity Protein Scribble for Podocyte Differentiation and Maintenance. PLoS One 7, (2012).
mouse
IHC (frozen)
Niethamer, T. K. et al. Oral monosaccharide therapies to reverse renal and muscle hyposialylation in a mouse model of GNE myopathy. Mol. Genet. Metab. -107, 748-755 (2012).
mouse
WB
Kakani, S. et al. The Gne M712T Mouse as a Model for Human Glomerulopathy. Am. J. Pathol. 180, 1431-1440 (2012).
mouse
WB
Wagner, N. et al. The podocyte protein nephrin is required for cardiac vessel formation. Hum. Mol. Genet. 20, 2182-2194 (2011).
mouse
IHC (frozen)
IHC (paraffin)
Gödel, M. et al. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J. Clin. Invest. 121, 2197-2209 (2011).
mouse
IHC (frozen)
Inoki, K. et al. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J. Clin. Invest. 121, 2181-2196 (2011).
human
IHC (frozen)
Puliti, A. et al. Albuminuria and Glomerular Damage in Mice Lacking the Metabotropic Glutamate Receptor 1. Am. J. Pathol. 178, 1257-1269 (2011).
mouse
WB
IHC (frozen)
ICC-IF
Matsusaka, T. et al. Podocyte injury damages other podocytes. J. Am. Soc. Nephrol. 22, 1275-85 (2011).
mouse
IHC (paraffin)
Matsusaka, T. et al. Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection. Am. J. Physiol. - Ren. Physiol. 300, F792-800 (2011).
mouse
WB
IHC (paraffin)
Meyer-Schwesinger, C. et al. Nephrotic Syndrome and Subepithelial Deposits in a Mouse Model of Immune-Mediated Anti-Podocyte Glomerulonephritis. J. Immunol. 187, 3218-3229 (2011).
mouse
IHC (paraffin)
Matsusaka, T. et al. ARB Protection Against Podocyte-Induced Sclerosis is Podocyte AT1-Independent. Hypertension 55, 967-973 (2010).
mouse
IHC (paraffin)
Li, Y. et al. Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis. J. Am. Soc. Nephrol. 20, 1907-18 (2009).
mouse
WB
IHC (frozen)
Turk, T. et al. BMP Signaling and Podocyte Markers Are Decreased in Human Diabetic Nephropathy in Association With CTGF Overexpression. J. Histochem. Cytochem. 57, 623-631 (2009).
human
IHC (paraffin)
Takabatake, Y. et al. The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature. J. Am. Soc. Nephrol. 20, 1714-23 (2009).
mouse
IHC (frozen)
Collino, F. et al. Preeclamptic sera induce nephrin shedding from podocytes through endothelin-1 release by endothelial glomerular cells. Am. J. Physiol. - Ren. Physiol. 294, 1185-1194 (2008).
human
WB
ICC-IF
Favaro, E. et al. Hyperglycemia Induces Apoptosis of Human Pancreatic Islet Endothelial Cells Effects of Pravastatin on the Akt Survival Pathway. Am. J. Pathol. 173, 442-450 (2008).
human
WB
IP
Uchida, K. et al. Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis. Kidney Int. 73, 926-932 (2008).
human
IHC
Wagner, K.-D. et al. Report An Inducible Mouse Model for PAX2-Dependent Glomerular Disease: Insights into a Complex Pathogenesis. Curr. Biol. 16, 793-800 (2006).
human
IHC
Bussolati, B. et al. Statins Prevent Oxidized LDL-Induced Injury of Glomerular Podocytes by Activating the Phosphatidylinositol 3-Kinase/ AKT-Signaling Pathway. J. Am. Soc. Nephrol.- JASN -16, 1936-1947 (2005).
human
ICC-IF