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anti-Neurokinin A rabbit polyclonal, serum

Neurokinin A arises upon cleavage of the substance P precurser and occurs in the central and peripheral nervous system. Positive staining is particularly numerous in the gastrointestinal tract.
Cat. No.: 16051
Quantity:  50 µL

Delivery Time: usually 1-7 working days

€411.00
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Product description

Host rabbit
Antibody Type polyclonal
Immunogen Neurokinin A/Substance K (Peninsula), conjugated to BSA
Purification undiluted antiserum
Conjugate unconjugated
Formulation lyophilized; reconstitute in 100 µl dist. water
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human, pig, rat

Applications

Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:200 - 1:800
Immunohistochemistry (IHC) - paraffin 1:200 - 1:800 (microwave treatment recommended)

Background

Details

Neurokinin A/Substance K represents a member of the tachykinin family of peptides. Neurokinin A, which arises by cleavage of the substance P precursor, occurs in neurons in the central and peripheral nervous systems, and is particularly numerous in the gastrointestinal tract. The biological actions of neurokinin A are similar to those of substance P, and include vasodilation and stimulation of smooth muscle contraction.
Absorption with 10-100 µg NKA per ml diluted antiserum abolishes the staining, while substance P does not.

Positive control: Formalin-fixed paraffin sections of rat colon.

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