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rat colon (courtesy of J.Heß, University Hospital Heidelberg) Zoom

rat colon (courtesy of J.Heß, University Hospital Heidelberg)

anti-p62 / SQSTM1 (N-terminus) guinea pig polyclonal, serum

Human p62 protein, present in intracytoplasmic inclusions is found in many tissues and cells, serving probably a common cellular signal transduction mechanism.
application_confirmed highly_published external_validation
Cat. No.: GP62-N
Quantity:  100 µL

Delivery Time: usually 1-7 working days

$337.00
Excl. 19% Tax, excl. Shipping Cost

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Specifications

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Product description

Host guinea pig
Antibody Type polyclonal
Immunogen N-terminal domain (20 amino acids: MAS LTV KAY LLG KED AAR EI-C) of human p62 protein, coupled to KLH
Purification stabilized antiserum
Conjugate unconjugated
Formulation contains 0.09% sodium azide and 0.5% BSA
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
UniprotID Q13501
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity bovine, human, mouse, rat

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:100 -1:500
Immunohistochemistry (IHC) - paraffin 1:100 -1:500 (microwave treatment recommended)
Western Blot (WB) 1:1,000

Background

Details

Reactive polypeptide (Specificity): Human 62 kD (p62) protein, present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. p62 protein has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism. The antiserum stains also neurofibrillary tangles in the brain of patients suffering from Alzheimer’s disease.

Reference

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