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anti-Peptide YY guinea pig polyclonal, serum

Peptide YY is produced in glicentin cells of the gut. It can be localized in the rectum, colon and ileum, and less abundant in the jejunum and duodenum. PYY may occur in endocrine tumors of the pancreas and the rectum.
Cat. No.: 16066
Quantity:  50 µL

Delivery Time: usually 1-7 working days

€245.00
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Product description

Host guinea pig
Antibody Type polyclonal
Immunogen Synthetic porcine peptide YY (Peninsula)
Purification undiluted antiserum
Conjugate unconjugated
Formulation lyophilized; reconstitute in 100 µl dist. water
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity cat, mouse, rat

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) 1:1,500 - 1:2,500
Immunohistochemistry (IHC) - frozen 1:1,500 - 1:2,500
Immunohistochemistry (IHC) - paraffin 1:1,500 - 1:2,500 (microwave treatment recommended)

Background

Details

The intestinal peptide YY is related to the PP-family of peptides and occurs in the glicentin cells in the gut. They are numerous in the rectum, colon, and ileum and few in the duodenum and jejunum. PYY has hormone-like action, inhibits gut motility and pancreatic exocrine secretion and cause vasoconstriction.
PYY may occur in endorine tumors of the pancreas and of the rectum. Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining.
Positive control: frozen sections of rat intestine

Reference

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