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anti-RAP mouse monoclonal, 7F1, lyophilized w/o sodium azide, purified

The antibody recognizes the 39 kD low density lipoprotein receptor-associated protein (RAP). No cross-reaction with rabbit or mouse RAP.
Cat. No.: 61068
Quantity:  50 µg

Delivery Time: usually 1-7 working days

€234.00
Excl. 19% Tax, excl. Shipping Cost

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Specifications

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone 7F1
Immunogen human RAP
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation lyophilized; reconstitute in 1 mL dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Intended use Research use only
Tested species reactivity human

Applications

Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:20
Immunohistochemistry (IHC) - paraffin 1:20 (microwave treatment recommended)
Receptor Binding Assays assay dependent
Western Blot (WB) assay dependent

Background

Details

7F1 reacts with the 39 kDa RAP protein, which is cosynthesized with human LRP/a2MR (low density lipoprotein receptor-related protein / a2-macro-globulin receptor). It inhibits the binding of ligands, e.g. tPA, uPA, VLDL, liproprotein lipase, and a2-macroglobulin-proteinase complexes to LRP/a2MR.

Reference

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