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Product description
| Host | rabbit |
|---|---|
| Antibody Type | polyclonal |
| Immunogen | recombinant human RAP (receptor-associated protein) |
| Purification | stabilized antiserum |
| Conjugate | unconjugated |
| Formulation | contains 0.09% sodium azide and 0.5% BSA |
| Storage | short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles |
| No. of experiments | ≤ 500 (IHC, 50 µl/slide) |
| Note | centrifuge prior to opening |
| Intended use | Research use only |
| Tested species reactivity | chicken, human, rat |
Applications
| Tested applications | Tested dilutions |
|---|---|
| Immunohistochemistry (IHC) - frozen | 1:50 – 1:100 |
| Immunohistochemistry (IHC) - paraffin | 1:50 – 1:100 (microwave treatment recommended) |
| Receptor Binding Assays | assay dependent |
| Western Blot (WB) | assay dependent |
Background
Details
The antibody binds to an epitope of the C-terminal part of RAP, a sequence common to the human VLDL receptor superfamily (glycoprotein 330 and LRP), the chicken oocyte receptor for VLDL and vitellogenin (LR8), and glycoprotein 330/megalin from rat. No reaction with LDL receptor. The antibody interferes with binding of VLDL and vitellogenin receptor. Binding is Ca2+-dependent with LR8.
Antigen recognized in species:
| human | RAP, CD91 (LRP), VLDL-R |
| chicken | LR8 |
| rat | gp330 |
Reference
There are currently no references for this product.
