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anti-Vasoactive Intestinal Peptide guinea pig polyclonal, serum

VIP is localized in nerve fibers in the central and peripheral nervous system. It is found in neuroblastomas of endocrine tumors in the pancreas. The antibody is raised against synthetic human VIP.
Cat. No.: 16071
Quantity:  50 µL
No. of experiments:  ≤ 4000 (IHC, 50 µl/slide)

Delivery Time: usually 1-7 working days

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Product description

Host guinea pig
Antibody Type polyclonal
Immunogen synthetic human VIP (Peninsula, #7161)
Purification undiluted antiserum
Conjugate unconjugated
Formulation lyophilized; reconstitute in 100 µl dist. water
Storage short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/ thaw cycles
No. of experiments ≤ 4000 (IHC, 50 µl/slide)
Intended use Research use only
Tested species reactivity cat, guinea pig, human, pig, rabbit, rat


Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:1,000 - 1:2,000
Immunohistochemistry (IHC) - paraffin 1:1,000 - 1:2,000 (microwave treatment recommended)



VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining, while PHI does not.
Positive control: Stefanini-fixed frozen sections of rat intestine


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