Antibodies

In immunoblots of cytoskeletal preparations from human skin the antibody reacts specifically with a 160 kD polypeptide typical for Desmoglein 1. In immunolocalisation studies the monoclonal desmoglein 1 antibody shows typical staining of suprabasal layers of the epidermis and special regions of fetal and anagen hair follicles. The staining pattern observed corresponds to those obtained with pemphigus foliaceus patient sera. Learn More

The antibody recognizes the nucleolar helicase protein NOH61 (61 kD), a constitutive nucleolar protein which has been highly conserved during evolution. It stains specifically the granular component of the nucleolus in interphase cells. Learn More

The antibody recognizes a 38kD nucleolar protein (NO38) in Xenopus (also termed numatrin, B23, nucleophosmin, in other species). NO-185 stains specifically the granular component of the nucleolus and small nucleolar dots in interphase cells. During mitosis the protein is localized accumulated around the condensed chromosomes. Learn More

Recognizes a 125 kD nucleoplasmic protein (AND-1, acidic nucleoplasmic DNA-binding protein) in Xenopus, showing a dispersed, finely granular distribution pattern throughout the nucleoplasm. Learn More

p97 ATPase (VCP) is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with p97 subunit of 15S Mg2+-ATPase. Learn More

p97 ATPase (VCP) s implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with p97 subunit of 15S Mg2+-ATPase. Learn More