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Cell cycle & apoptosis

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  • anti-Cyclin-Dependent Kinase 4 mouse monoclonal, DCS-35, supernatant

    The anti-Cyclin-Dependent Kinase 4 (Cdk4)monoclonal DCS-35 antibody reacts specifically with Cdk4 kinase, active predominantly in G1 of the cell cycle. No cross-reaction with other Cdks or cyclins. Especially useful for immunoprecipitation of the Cdk4/cyclin complex. Learn More
    Product information:
    Cat. No.
    65195
    Quantity
    5 mL
    Delivery time
    usually 1-7 working days
    Application
    IP, WB
    Reactivity
    human, mouse, pig, rat
    anti-Cyclin-Dependent Kinase 4 mouse monoclonal, DCS-35, supernatant
    €129.00

  • anti-Cyclin-Dependent Kinase 6 mouse monoclonal, DCS-83, lyophilized, purified

    The anti-Cyclin-Dependent Kinase 6 (Cdk6) monoclonal DCS-83 antibody reacts specifically with Cdk6 kinase, which can substitute for Cdk4. Cdk6 is highly expressed in some lymphoid tumor and sarcoma cell lines (ML-1 and U-2-OS resp.). Positive staining found in head and neck tumors. Learn More
    Product information:
    Cat. No.
    610103
    Quantity
    100 µg
    Delivery time
    usually 1-7 working days
    Application
    IHC, IP, WB
    Reactivity
    human
    anti-Cyclin-Dependent Kinase 6 mouse monoclonal, DCS-83, lyophilized, purified
    €153.00

  • anti-Cyclin-Dependent Kinase 6 mouse monoclonal, DCS-83, supernatant

    The anti-Cyclin-Dependent Kinase 6 (Cdk6) monoclonal DCS-83 antibody reacts specifically with Cdk6 kinase, which can substitute for Cdk4. Cdk6 is highly expressed in some lymphoid tumor and sarcoma cell lines (ML-1 and U-2-OS resp.). Positive staining found in head and neck tumors. Learn More
    Product information:
    Cat. No.
    651103
    Quantity
    5 mL
    Delivery time
    usually 1-7 working days
    Application
    IHC, IP, WB
    Reactivity
    human
    anti-Cyclin-Dependent Kinase 6 mouse monoclonal, DCS-83, supernatant
    €160.00

  • anti-p16 Protein mouse monoclonal, DCS-50, lyophilized, purified

    p16, a protein implicated in cancer development, is a specific inhibitor for Cdk4 and Cdk6. It binds to phosphorylated Cdk-cyclin complex which is recognized by DCS-50. Learn More
    Product information:
    Cat. No.
    61074
    Quantity
    50 µg
    Delivery time
    usually 1-7 working days
    Application
    FACS, ICC/IF, IHC, IP, WB
    Reactivity
    human
    anti-p16 Protein mouse monoclonal, DCS-50, lyophilized, purified
    €160.00

  • anti-p16 Protein mouse monoclonal, DCS-50, supernatant

    p16, a protein implicated in cancer, is a specific inhibitor for Cdk4 and Cdk6. It binds to phosphorylated Cdk-cyclin complex which is recognized by DCS-50. Learn More
    Product information:
    Cat. No.
    65174
    Quantity
    5 mL
    Delivery time
    usually 1-7 working days
    Application
    ICC/IF, IHC, WB
    Reactivity
    human
    anti-p16 Protein mouse monoclonal, DCS-50, supernatant
    €129.00

  • anti-p21 Protein mouse monoclonal, WA-1, supernatant

    p21 immunostaining is most often used in combination with p53 to confirm the presence of a p53 mutation. p53 overexpression in combination with low or absent p21 expression is consistent with a p53 mutation. Learn More
    Product information:
    Cat. No.
    16081
    Quantity
    1 mL
    Delivery time
    usually 1-7 working days
    Application
    IHC, WB
    Reactivity
    human (most mammals)
    anti-p21 Protein mouse monoclonal, WA-1, supernatant
    €260.00

  • anti-p34cdc-2 mouse monoclonal, POH-1, ascites fluid

    The anti-p34cdc-2 antibody detects the three bands within the 34kD region corresponding to the p34 protein and its cleavage products. p34cdc-2 initiates entry of cells into mitosis by promoting nuclear envelope breakdown. The expression reflects the proliferation potential of cells. Learn More
    Product information:
    Cat. No.
    16097
    Quantity
    1 mL
    Delivery time
    usually 1-7 working days
    Application
    IHC, WB
    Reactivity
    human
    anti-p34cdc-2 mouse monoclonal, POH-1, ascites fluid
    €227.00

  • anti-p53 mouse monoclonal, BP 53,12, ascites

    The gene coding for p53 oncoprotein is located on chromosome 17p. Allele loss at this hromosome site has frequently been seen in many tumours including lung, colon, breast and brain. Expression of p53 oncoprotein was not detected in normal mucosa, whereas mutation results in a detectable expression of the p53 protein. It is therefore suggested that immunocytochemical detection of p53 protein is an indication for malignancy. Learn More
    Product information:
    Cat. No.
    18314
    Quantity
    1 mL
    Delivery time
    usually 1-7 working days
    Application
    ICC/IF, IHC
    Reactivity
    human
    anti-p53 mouse monoclonal, BP 53,12, ascites
    €228.00

  • anti-p53 Protein mouse monoclonal, Bp53.11, lyophilized, purified

    The anti-p53 antibody reacts with wild-type and mutant forms of human p53 antigen (Immunogen: transcription domain within the NH2-terminal region). Stains 60% of investigated carcinomas of e.g. breast, colon, pancreas. Learn More
    Product information:
    Cat. No.
    61039
    Quantity
    50 µg (2 x 25 µg vials)
    Delivery time
    usually 1-7 working days
    Application
    ELISA, ICC/IF, IHC, IP, WB
    Reactivity
    human
    p53 staining in human squamous cell carcinoma (image courtesy of J.Heß, University Hospital Heidelberg)
    €212.00

  • anti-p53 Protein mouse monoclonal, Bp53.11, purified

    The anti-p53 antibody reacts with wild-type and mutant forms of human p53 antigen (Immunogen: transcription domain within the NH2-terminal region). Stains 60% of investigated carcinomas of e.g. breast, colon, pancreas. Learn More
    Product information:
    Cat. No.
    61039L
    Quantity
    100 µL
    Delivery time
    usually 1-7 working days
    Application
    ELISA, ICC/IF, IHC, IP, WB
    Reactivity
    human
    p53 staining in human squamous cell carcinoma (image courtesy of J.Heß, University Hospital Heidelberg)
    €339.00

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