Call +49 6221 8278-0

PROGEN - passion for research

close×

mouse fat tissue (courtesy of J.Heß, University Hospital Heidelberg) Zoom

mouse fat tissue (courtesy of J.Heß, University Hospital Heidelberg)

anti-Perilipin 1 (N-terminus) mouse monoclonal, PERI 112.17, supernatant

The antibody reacts specifically with perilipin 1 located at the surface of intracellular storage lipid droplets present e.g. in the adrenal gland, sebaceous gland, adipocytes of white and brown adipose tissue and cultured cells such as 3T3-L1 adipocytes and cultured steroidogenic adrenal cortical and Leydig cells.
highly_published external_validation
Cat. No.: 651156
Quantity:  5 mL

Delivery Time: usually 1-7 working days

€212.00
Excl. 19% Tax, excl. Shipping Cost

Call us now for more information on our products: +49 6221 8278-0

Any more questions?
PRODUCT REQUEST

Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone PERI 112.17
Immunogen synthetic peptide of perilipin / PLIN1 (duplicated N-terminus of perilipin; aa 1-20)
Purification hybridoma cell culture supernatant
Conjugate unconjugated
Formulation contains 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
UniprotID O60240
Tested species reactivity bovine, human, mouse, rat
Intended use Research use only

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen ready-to-use
Immunohistochemistry (IHC) - paraffin ready-to-use (microwave treatment recommended)
Western Blot (WB) assay dependent

Background

Details

Perilipins build a family of phosphoproteins. The predominant forms in adipocytes, PLIN1 A and B arise by alternative RNA splicing from a single gene, generating polypeptides of 57 and 46 kD, respectively. The N-terminus, however, remains unchanged.

The antibody reacts specifically with all PLIN1 variants located at the surface of intracellular storage lipid droplets present e.g. in the adrenal gland, sebaceous gland, adipocytes of white and brown adipose tissue and cultured cells such as 3T3-L1 adipocytes and cultured steroidogenic adrenal cortical and Leydig cells. It also is a useful pathological marker for steatogenesis e.g. in liver. It does not cross-react with adipophilin (ADRP, also named PLIN2) or TIP47 (also named PLIN3) proteins (or additional members of the PLIN/PAT-family, e.g. MLDP or OXPAT/PAT-1, also named PLIN5 or LSDP5).

Tested reactivity on cultured cell lines: Several human carcinoma cell lines; 3T3-L1 adipocytes.

Learn more about PROGEN Perilipin antibodies.

Reference

Material safety data sheet

Please complete the form below to request a material safety data sheet

Personal Info

* Required Fields

Product Request

Personal Info

* Required Fields