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anti-RAP rabbit polyclonal, serum

The antibody recognizes the 39 kD low density lipoprotein receptor-associated protein (RAP, pleo-lipoprotein receptor). No reaction with LDL receptor.
Cat. No.: 61098
Quantity:  250 µL

Delivery Time: usually 1-7 working days

€196.00
Excl. 19% Tax, excl. Shipping Cost

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Specifications

Product description

Host rabbit
Antibody Type polyclonal
Immunogen recombinant human RAP (receptor-associated protein)
Purification stabilized antiserum
Conjugate unconjugated
Formulation contains 0.09% sodium azide and 0.5% BSA
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Note centrifuge prior to opening
Intended use Research use only
Tested species reactivity chicken, human, rat

Applications

Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:50 – 1:100
Immunohistochemistry (IHC) - paraffin 1:50 – 1:100 (microwave treatment recommended)
Receptor Binding Assays assay dependent
Western Blot (WB) assay dependent

Background

Details

The antibody binds to an epitope of the C-terminal part of RAP, a sequence common to the human VLDL receptor superfamily (glycoprotein 330 and LRP), the chicken oocyte receptor for VLDL and vitellogenin (LR8), and glycoprotein 330/megalin from rat. No reaction with LDL receptor. The antibody interferes with binding of VLDL and vitellogenin receptor. Binding is Ca2+-dependent with LR8.

Antigen recognized in species:

human RAP, CD91 (LRP), VLDL-R
chicken LR8
rat gp330

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