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anti-Synaptophysin mouse monoclonal, SY38, prediluted, purified

The anti-synaptophysin antibody SY38 stains neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas and neuroendocrine tumors of epithelial origin, e.g. pancreatic islet cell carcinoma, brochial and gastrointestinal carcinoids.
Cat. No.: 19012
Quantity:  1 mL

Delivery Time: usually 1-7 working days

€207.00
Excl. 19% Tax, excl. Shipping Cost

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Product description

Host mouse
Antibody Type monoclonal
Isotype IgG1
Clone SY38
Immunogen Synaptophysin from presynaptic vesicles, prepared from bovine brain
Purification protein A affinity chromatography
Conjugate unconjugated
Formulation PBS with 0.5% BSA and 0.09% sodium azide
Storage short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity human
Note centrifuge prior to opening
Intended use Research use only

Applications

Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) assay dependent
Immunohistochemistry (IHC) - frozen 1:10 (in no case protease pretreatment)
Immunohistochemistry (IHC) - paraffin 1:10 (in no case protease pretreatment)
Western Blot (WB) assay dependent

Background

Details

The antibody recognizes presynaptic vesicles of neurons of brain, spinal cord, retina neuromuscular junctions, small vesicles of adrenal medulla and pancreatic islets. The antibody can be used for the characterisation of neuroendocrine tumors. Immunoblotting: the antibody predominantly reacts with a 38 kD transmembrane glycoprotein from synaptic vesicles.

Positive control: adrenal peochromcytoma, pancreatic islet cell neoplasm.

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